Table 2

Modifications of LFTs over time in patients with SSc-ILD treated with nintedanib

Baseline6 monthsP valueBaseline12 monthsP value
%predicted FVC65±1667±17 (49 patients)0.14164±1862±19 (40 patients)0.416
%predicted TLC65±1562±15 (49 patients)0.11864±1761±17 (40 patients)0.096
% predicted DLCO42±1843±18 (49 patients)0.96137±1634±15 (40 patients)0.019
  • DLCO, diffusing capacity for carbon monoxide; FVC, forced vital capacity; ILD, interstitial lung disease; LFTs, lung function tests; SSc, systemic sclerosis; TLC, total lung capacity.