Table 3

Univariate and multivariate analysis of parameters associated with a clinCumESSDAI ≥5

CharacteristicUnivariate analysisMultivariate analysis*
OR95% CIP valueOR95% CIP value
Origin
 Caucasian
 Afro-Caribbean1.210.56 to 2.680.621.530.61 to 3.940.4
 Sub-Saharan2.581.26 to 5.590.0122.651.06 to 6.940.040
Follow-up duration1.061.02 to 1.110.0091.040.99 to 1.100.11
Age at Sjögren’s diagnosis0.9780.960 to 0.9960.0210.980.96 to 1.010.2
Sex
 Female
 Male0.700.24 to 2.020.51
Oral dryness1.750.79 to 3.960.17
Eye dryness1.140.58 to 2.230.71
Shiermer abnormal0.980.50 to 1.920.95
Low salivary flux1.010.50 to 2.040.98
Chisholm score
 0–2
 3–41.040.50 to 2.130.91
Gammaglobulins titre (g/L)1.040.99 to 1.080.110.980.92 to 1.040.4
Rheumatoid factor2.451.43 to 4.250.0012.501.28 to 4.960.008
anti-SSA1.510.81 to 2.840.20
anti-SSB1.440.84 to 2.510.19
anti-RNP9.811.86 to 1810.03011.11.88 to 2120.028
Cryoglobulin2.641.28 to 5.800.0111.820.81 to 4.280.2
Low C41.550.81 to 3.030.19
  • *Mutlivariate analysis adjusted on ancestry, follow-up duration, age at Sjögren’s diagnosis, gammaglobulins titre, rheumatoid factor, cryoglobulin and anti-RNP positivity.

  • ESSDAI, EULAR Sjögren’s Syndrome Disease Activity Index.