ROC results for priority anchors in derivation of ‘low/minimal symptom severity’
| Priority anchor | Time point | AUC | Optimal cut-off point threshold | Sensitivity | Specificity |
| Phase IIb analyses | |||||
| PaGA (stratification A) | Week 24 | 0.74 | 4.3 | 0.60 | 0.74 |
| PaGA (stratification B) | Week 24 | 0.83 | 3.0 | 0.67 | 0.88 |
| Pooled analyses | |||||
| PhGA (stratification B) | Week 24 | 0.69 | 3.3 | 0.54 | 0.80 |
| PaGA (stratification B) | Week 24 | 0.82 | 3.7 | 0.90 | 0.67 |
AUC, area under the curve; PaGA, Patient Global Assessment; PhGA, Physician’s Global Assessment; ROC, receiver operating characteristic.