Table 3

ROC results for priority anchors in derivation of ‘low/minimal symptom severity’

Priority anchorTime pointAUCOptimal cut-off point thresholdSensitivitySpecificity
Phase IIb analyses
PaGA (stratification A)Week 240.744.30.600.74
PaGA (stratification B)Week 240.833.00.670.88
Pooled analyses
PhGA (stratification B)Week 240.693.30.540.80
PaGA (stratification B)Week 240.823.70.900.67
  • AUC, area under the curve; PaGA, Patient Global Assessment; PhGA, Physician’s Global Assessment; ROC, receiver operating characteristic.