Table 2

Frequencies of first DMARD (regardless of type) and b/tsDMARD, respectively, started after methotrexate at any time point during the follow-up

First DMARD (any) after methotrexateFirst b/tsDMARDs
DMARD PsA RA PsA RA
Sulfasalazine, N (%)540 (32)601 (30)
Etanercept, N (%)367 (22)352 (18)498 (37)572 (39)
Adalimumab, N (%)336 (20)240 (12)450 (34)348 (24)
Leflunomid, N (%)154 (9)136 (7)
Hydroxychloroquine, N (%)21 (1)264 (13)
Infliximab, N (%)95 (6)135 (7)126 (9)175 (12)
Golimumab, N (%)52 (3)62 (3)66 (5)80 (6)
Certolizumab pegol, N (%)23 (1)53 (3)37 (3)89 (6)
Apremilast, N (%)74 (4)0 (0)116 (9)0 (0)
Abatacept, N (%)2 (0)29 (1)3 (0)47 (3)
Tocilizumab, N (%)1 (0)30 (2)1 (0)41 (3)
Baricitinib, N (%)1 (0)20 (1)1 (0)31 (2)
Azathioprine, N (%)5 (0)14 (1)
Rituximab, N (%)0 (0)35 (2)1 (0)58 (5)
Secukinumab, N (%)8 (0)0 (0)12 (1)0 (0)
Tofacitinib, N (%)4 (0)3 (0)6 (0)4 (0)
Chloroquine, N (%)0 (0)4 (0)
Anakinra, N (%)1 (0)2 (0)1 (0)2 (0)
Ciklosporine A, N (%)3 (0)0 (0)
Mycophenolate mofetil, N (%)1 (0)2 (0)
Upadacitinib, N (%)2 (0)1 (0)3 (0)1 (0)
Ustekinumab, N (%)4 (0)0 (0)5 (0)0 (0)
Ixekizumab, N (%)2 (0)0 (0)2 (0)0 (0)
Auranofin, N (%)0 (0)1 (0)
Sodium aurothiomalate, N (%)0 (0)1 (0)
Sarilumab, N (%)0 (0)0 (0)0 (0)2 (0)
Guselkumab, N (%)0 (0)0 (0)1 (0)0 (0)
  • b/tsDMARD, disease-modifying antirheumatic drug; DMARD, disease-modifying antirheumatic drug; PsA, psoriatic arthritis; RA, rheumatoid arthritis.