Change in PROMIS29+MSx from BL to EOP by domain (n=202)
| Mean at BL | Mean at EOP | Change | P value | |
| Ability to participate in social roles and activities* | 46.5 | 52.1 | 5.6 | <0.0001 |
| Cognitive function* | 49.3 | 52.3 | 3.0 | <0.0001 |
| Ability to manage symptoms* | 43.3 | 49.7 | 6.4 | <0.0001 |
| Physical function* | 44.4 | 47.4 | 3.0 | <0.0001 |
| Anxiety† | 55.7 | 51.5 | −4.2 | <0.0001 |
| Depression† | 51.3 | 48.2 | −3.1 | <0.0001 |
| Fatigue† | 58.3 | 50.5 | −7.8 | <0.0001 |
| Pain interference† | 56.9 | 51.5 | −5.5 | <0.0001 |
| Sleep disturbance† | 53.4 | 47.7 | −5.7 | <0.0001 |
| Pain intensity†‡ | 4.0 | 2.5 | −1.4 | <0.0001 |
*Higher score indicates improvement.
†Lower score indicates improvement.
‡Pain intensity was measured on a 0–10 VAS.
BL, baseline; EOP, end of programme; VAS, Visual Analogue Scale.