‘Good Responders’ | ‘Suboptimal Responders’ | ‘Non-Responders’ | ||||
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Age/years | 0.9 (0.85 to 0.95) | 0.001 | 0.91 (0.86 to 0.96) | 0.001 | 0.91 (0.86 to 0.97) | 0.001 |
Male (ref: female) | 11.23 (2.12 to 59.62) | 0.005 | 1.71 (0.26 to 11.13) | 0.577 | 6.3 (1.37 to 28.96) | 0.018 |
SLE duration/years | 1.11 (0.96 to 1.28) | 0.172 | 1.13 (0.97 to 1.32) | 0.11 | 1.05 (0.91 to 1.21) | 0.517 |
New-onset LN (%) | 0.36 (0.09 to 1.49) | 0.159 | 2.01 (0.46 to 8.71) | 0.353 | 0.52 (0.14 to 1.94) | 0.329 |
LN (%) | ||||||
Mixed | ref | / | ref | / | ref | / |
I or II | / | / | / | / | 1.18 (0.11 to 12.49) | 0.889 |
III or IV | 0.92 (0.25 to 3.4) | 0.895 | 1.23 (0.35 to 4.31) | 0.748 | 0.57 (0.16 to 1.95) | 0.367 |
V | 2.72 (0.64 to 11.52) | 0.174 | 12.83 (2.93 to 56.31) | 0.001 | 3.02 (0.82 to 11.04) | 0.095 |
Acute kidney injury (%) | 1.6 (0.2 to 12.89) | 0.661 | 0.66 (0.09 to 4.65) | 0.676 | 1.06 (0.14 to 7.86) | 0.952 |
Activity index | 1.05 (0.89 to 1.24) | 0.525 | 1.08 (0.93 to 1.26) | 0.308 | 1.03 (0.89 to 1.2) | 0.67 |
Karyorrhexis | 0.64 (0.13 to 3.3) | 0.598 | 8.17 (1.51 to 44.17) | 0.015 | 1.14 (0.25 to 5.27) | 0.863 |
Cell crescents | 7.9 (1.18 to 52.69) | 0.033 | 0.1 (0.01 to 0.8) | 0.03 | 1.87 (0.28 to 12.58) | 0.52 |
Glomerulosclerosis | 3564.23 (339.14 to 37 458.2) | <0.001 | 158.05 (19.61 to 1274.06) | <0.001 | 14.11 (8.31 to 23.96) | <0.001 |
Tubular atrophy | 1.17 (1.03 to 1.32) | 0.012 | 1.13 (1 to 1.28) | 0.052 | 1.2 (1.06 to 1.35) | 0.004 |
Tubulointerstitial sclerosis (%) | 0.14 (0.02 to 0.74) | 0.021 | 0.22 (0.04 to 1.14) | 0.071 | 0.1 (0.02 to 0.52) | 0.006 |
24-hour urine protein (g/day) | 2.2 (1.45 to 3.35) | <0.001 | 2.02 (1.33 to 3.07) | 0.001 | 1.86 (1.22 to 2.84) | 0.004 |
Albumin (g/L) | 0.9 (0.83 to 0.98) | 0.012 | 0.83 (0.76 to 0.91) | <0.001 | 0.94 (0.88 to 1.02) | 0.129 |
Urine red blood cells/high power | 1.02 (1 to 1.04) | 0.059 | 1.03 (1.01 to 1.05) | 0.009 | 1 (0.97 to 1.03) | 0.933 |
Serum creatinine (umol/L) | 1 (0.98 to 1.02) | 0.871 | 1.01 (0.99 to 1.03) | 0.471 | 1.01 (0.99 to 1.03) | 0.379 |
LN, lupus nephritis; SLE, systemic lupus erythematosus.