Relationship between ILD patterns and clinical course in patients with anti-MDA5+DM
| Variables | RPILD | Non-RPILD | P value |
| Radiological pattern, n (%)* | |||
| NSIP | 38 (21.5) | 49 (37.4) | 0.002 |
| OP | 79 (44.6) | 63 (48.1) | 0.547 |
| NSIP+OP | 47 (26.6) | 14 (10.7) | 0.001 |
| DAD | 5 (2.8) | 0 (0.0) | 0.074 |
| UIP | 2 (1.1) | 0 (0.0) | 0.510 |
| Unclassifiable pattern | 4 (2.3) | 3 (2.3) | 1.000 |
| Other types | 2 (1.1) | 2 (1.5) | 1.000 |
| Histopathological pattern, n (%)† | |||
| NSIP | 1 (14.3) | 6 (60.0) | – |
| OP | 0 (0.0) | 0 (0.0) | – |
| NSIP+OP | 4 (57.1) | 4 (40.0) | – |
| DAD | 1 (14.3) | 0 (0.0) | – |
| AFOP | 1 (14.3) | 0 (0.0) | – |
*Data available for 308 patients.
†Data available for 17 patients.
AFOP, acute fibrinous and organising pneumonia; anti-MDA5+DM, anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis; DAD, diffuse alveolar damage; ILD, interstitial lung disease; NSIP, non-specific interstitial pneumonia; OP, organising pneumonia; RPILD, rapidly progressive interstitial lung disease; UIP, usual interstitial lung disease.