Baseline characteristics of CCP+ICI IA, CATCH-US and FLARE patients
| ICI-IA (N=12) | CATCH-US (N=39) | FLARE (N=24) | P value | |
| Age in years, mean (SD) | 71.0 (8.3) | 48.2 (14.6) | 64.27 (10.9) | p<0.001 |
| Female sex | 7 (58%) | 33 (85%) | 22 (92%) | 0.08 |
| White/Caucasian | 9 (75%) | 27 (69%) | 19 (79%) | 0.8 |
| Symptom duration in months, median (IQR) | 3.7(1.0,11.3) | 6.7(4.0,9.7) | 232(184,376) | p<0.001 |
| RF positive | 1 (8%) | 27 (71%) | 13 (54%) | p=0.002 |
| CCP level (units/mL), median (IQR) | 42.2 (29.4,70.5) | 250 (107.5,251.0) | 239 (28.5,251.0) | 0.06 |
| Obese (BMI≥30) | 3 (25%) | 9 (23%) | 7 (29%) | 0.2 |
| Current/past smoker | 8 (67%) | 14 (38%) | 13 (54%) | 0.2 |
Bolded values are statistically significant.
.BMI, body mass index; CATCH, Early RA cohort; CCP, cyclic citrullinated peptide; FLARE, Late RA cohort; ICI-IA, immune checkpoint inhibitor inflammatory arthritis; RF, rheumatoid factor.