Table 3

Comparison of LEAF patients with or without significant fatigue

ParametersPatients with significant fatigue (n=987)Patients without significant fatigue (n=263)P value
Age, median (IQR)43 (34-52)41 (33-49.5)0.19
Female, n (%)954/992 (96.2)162/177 (91.5)0.01*
NRS disease activity, median (IQR)6 (3-7)3 (1-5)<0.0001*
NRS pain, median (IQR)6 (3.25-7)2 (1-4.5)<0.0001*
Score FiRST positive, n (%)379/611 (62.0)17/77 (22.1)<0.0001*
HADS anxiety, median (IQR)10 (7-14)7 (4-10)<0.0001*
HADS depression, median (IQR)8 (5-11)4 (2-7)<0.0001*
ISI, median (IQR)16 (11-19)10 (5-15)<0.0001*
High level of stress, n (%)540/878 (69.4)53/118 (44.9)<0.0001*
Low level of physical activity, n (%)354/816 (43.4)46/128 (35.9)0.12
  • *P value<0.05.

  • FiRST, Fibromyalgia Rapid Screening Tool; HADS, Hospital Anxiety and Depression Scale; ISI, Insomnia Severity Index; NRS, Numerical Rating Scale.