Autoimmune disease | No of patients | |
Haematological | Total | 33 (40%) |
Idiopathic-acquired pure red cell aplasia | 1 | |
Immune thrombocytopaenic purpura | 8 | |
Acquired immune mediated thrombotic thrombocytopaenic purpura | 9 | |
Autoimmune haemolytic anaemia | 4 | |
Acquired haemophilia A | 9 | |
Red blood cell antibodies (inducing haemolytic transfusion reaction in sickle cell disease) | 1 | |
Idiopathic cold agglutinin disease | 1 | |
Rheumatological | Total | 19 (23%) |
Idiopathic inflammatory myopathy | 3 with: 2 MDA5-positive dermatomyositis with interstitial lung disease 1 SRP-positive immune mediated necrotising myopathy | |
Systemic lupus erythematosus | 10 with: 7 lupus nephritis 2 autoimmune haemolytic anaemia 1 cerebral vasculitis | |
ANCA-associated vasculitis | 4 with: 1 MPO-positive microscopic polyangiitis 3 PR3-positive granulomatosis with polyangiitis | |
Primary Sjögren’s disease | 2 with: 1 cryoglobulinaemia 1 hyperchylomicronaemia | |
Nephrological | Total | 21 (25%) |
Idiopathic nephrotic syndrome | 14 | |
PLA2R-positive membranous nephropathy | 1 | |
Focal segmental glomerulosclerosis | 3 | |
Minimal change disease | 3 | |
Neurological | Total | 8 (10%) |
Autoimmune encephalitis | 6 with 2 NMDA-R-positive 2 CASPR2-positive 2 without antibody | |
Chronic inflammatory demyelinating polyneuropathy | 1 | |
Seronegative myasthenia gravis | 1 | |
Other | Total | 2 (2%) |
Primary antiphospholipid syndrome | 1 | |
Anti-IFNγ antibodies and severe mycobacterium avium infection | 1 |
ANCA, anti-neutrophil cytoplasmic antibody; CASPR2, contactin associated protein-like 2; IFN, interferon; MDA5, melanoma differentiation-associated protein; MPO, myeloperoxidase; NMDA-R, N-methyl-D-aspartate receptor; PLA2R, phospholipase A2 receptor; PR3, proteinase 3; SRP, signal recognition particle.