Table 3

Covariate-adjusted odds of tinnitus, hearing loss, vertigo and sudden deafness among Sjogren’s syndrome versus comparison patients (n=81 064)

VariableOR (95% CIs)
TinnitusSudden deafnessHearing lossVertigo
Sjogren’s syndrome (unadjusted)1.678 (1.586–1.775)1.379 (1.146–1.659)1.709 (1.586–1.841)1.463 (1.351–1.584)
Sjogren’s syndrome (adjusted)*1.690 (1.596–1.788)1.368 (1.137–1.647)1.724 (1.598–1.859)1.473 (1.360–1.597)
Age1.019 (1.017–1.021)1.011 (1.004–1.018)1.037 (1.034–1.040)1.021 (1.018–1.024)
Sex0.798 (0.749–0.851)0.932 (0.765–1.136)1.139 (1.052–1.233)0.499 (0.450–0.552)
Monthly income
 <NT$15 841 (reference group)1.0001.0001.0001.000
 NT$15 841–25 0001.147 (1.059–1.242)0.947 (0.738–1.214)0.825 (0.747–0.912)1.185 (1.062–1.322)
 ≥NT$25 0011.165 (1.078–1.260)1.008 (0.792–1.284)0.937 (0.851–1.032)1.119 (1.005–1.247)
Geographic region
 Northern (reference group)1.0001.0001.0001.000
 Central1.185 (1.108–1.267)1.483 (1.197–1.838)1.038 (0.949–1.236)0.969 (0.881–1.065)
 Southern1.047 (0.964–1.137)1.197 (0.915–1.565)0.847 (0.757–0.948)0.928 (0.828–1.041)
 Eastern1.325 (1.049–1.673)0.829 (0.305–2.256)0.846 (0.594–1.206)1.113 (0.860–1.536)
Urbanisation level
 1 (reference group)1.0001.0001.0001.000
 21.047 (0.973–1.126)0.763 (0.604–0.963)0.948 (0.861–1.044)1.048 (0.946–1.160)
 31.067 (0.978–1.163)0.701 (0.528–0.930)0.885 (0.787–0.996)1.123 (0.996–1.268)
 41.015 (0.922–1.117)0.951 (0.714–1.267)1.069 (0.944–1.212)1.039 (0.908–1.188)
 50.961 (0.863–1.071)0.732 (0.515–1.039)0.991 (0.860–1.142)1.053 (0.908–1.221)
Hypertension1.191 (1.115–1.272)1.176 (0.951–1.454)1.154 (1.058–1.259)1.416 (1.292–1.552)
Diabetes0.975 (0.912–1.043)1.123 (0.908–1.389)1.039 (0.954–1.133)0.966 (0.882–1.058)
Hyperlipidaemia1.517 (1.428–1.613)1.464 (1.203–1.783)1.324 (1.222–1.434)1.613 (1.482–1.756)
Rheumatoid arthritis1.224 (1.110–1.351)1.085 (0.777–1.515)1.269 (1.114–1.446)1.296 (1.139–1.475)
  • *Adjusted for age, sex, monthly income, geographic region, urbanisation level, diabetes, hypertension, hyperlipidaemia and rheumatoid arthritis.