Table 3

Effect sizes of faecal microbiota transplantation (FMT) and treatment with TNF inhibitor (TNFi), respectively, on inflammation-associated plasma protein levels (Normalised Protein eXpression (NPX))

ProteinFMTTNF
Increased NPX
 IFN gamma0.5230.642
 AXIN10.452−1.075
 CCL250.4030.217
 OSM0.3900.074
 CCL40.376−0.609
Decreased NPX
 CCL19−0.443−0.274
 IL6−0.418−0.467
 FGF21−0.358−0.174
 IL22RA1−0.3380.247
 TRANCE−0.3260.003
  • Only top-five proteins with the largest increase (positive effect size) or decrease (negative effect size) in NPX value as a result of FMT are shown in this table.

  • CCL-25, C-C motif chemokine 25; FGF-21, fibroblast growth factor 21; IFN-γ, interferon-γ; IL-6, interleukin 6; IL-22 RA1, interleukin 22 receptor subunit alpha-1; TRANCE, TNF-related activation-induced cytokine.