Colchicine prescriptions and adaptations (n=62)
| Treatment plan | |
| Loading dose 1 mg first day, then 0.5 mg/day, n (%) | 9 (14.5%) |
| In patients on dialysis | 3/14 (21.4%) |
| 1 mg/day, n (%) | 6 (9.7%) |
| In patients on dialysis | 0 |
| ≤ 0.5 mg/day, n (%) | 47 (75.8%) |
| In patients on dialysis | 11/14 (78,6%) |
| Treatment duration in days, median (IQR) | 6 (3-11) |
| < 6 days, n (%) | 30 (48.4%) |
| 6–10 days, n (%) | 13 (21.0%) |
| > 10 days, n (%) | 19 (30.6%) |
| Initiation delay from microcrystalline attack in days, median (IQR) | 0 (0–1) |
| Within the first day, n (%) | 38 (61.4%) |
| The following day, n (%) | 12 (19.3%) |
| Other*, n (%) | 12 (19.3%) |
| Median, IQR (days) | 2 (2–3.5) |
| Colchicine dosage adaptation, n (%) | 17 (27.4%) |
| Transient decrease or discontinuation (poor tolerance, expert’s intervention or returning home) | 14/17 (82%) |
| Increase (ineffective or expert opinion)† | 3/17 (18%) |
*Including six reporting the start of the acute attack before hospitalisation or unknown.
†Without exceeding the dose of 1 mg/day.