Table 3

Colchicine prescriptions and tolerance according to CKD stage (n=62)

CKD stage G4 (eGFR 15–30 mL/min)39 (62.9%)
 Loading dose 1 mg first day, then 0.5 mg/day, n (%)5/39 (12.8%)
  Any side effect1 (20%)
 1 mg/day, n (%)6/39 (15.4%)
  Any side effect3/6 (50%)
 ≤ 0.5 mg/day, n (%)28/39 (71.8%)
  Any side effect8/28 (28.6%)
CKD stage G5 (eGFR<15 mL/min)9 (14.5%)
 Loading dose 1 mg first day, then 0.5 mg/day, n (%)1/9 (11.1%)
  Any side effect0
 1 mg/day, n (%)0
  Any side effect0
 ≤ 0.5 mg/day, n (%)8/9 (88.9%)
  Any side effect1/8 (12.5%)
Patients on dialysis14 (22.6%)
 Loading dose 1 mg first day, then 0.5 mg/day, n (%)3/14 (21.4%)
  Any side effect0
 1 mg/day, n (%)0
  Any side effect0
 ≤ 0.5 mg/day, n (%)11/14 (78,6%)
  Any side effect4/11 (36.4%)
  • CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate.