Table 4

cJADAS10 and components at the three major visits for each trajectory group in the Nordic juvenile idiopathic arthritis cohort

nBaselinen8-year follow-upN18-year follow-upP value*
Group 1 (MiDA-ID)
 cJADAS10701.7 (0–3.9)1010 (0–0.1)1470 (0–0.5)<0.00010.40
 Active joint count1680 (0–1.0)1680 (0–0)1670 (0–0)<0.00010.03
 PaGA840.5 (0–1.5)1230 (0–0)1510 (0–0.5)<0.00010.01
 PhGA730.5 (0–1.0)1030 (0–0)1630 (0–0)<0.00010.45
Group 2 (MiDA-MDA)
 cJADAS10552.2 (1.5–4.5)781.5 (0–3.7)944.0 (1.5–8.5)0.200.008
 Active joint count1040 (0–1.0)1010 (0–1.0)1040 (0–1.0)0.360.50
 PaGA650.5 (0–1.5)830.2 (0–1.2)952.0 (0.5–4.5)0.28<0.0001
 PhGA570.9 (0.3–1.2)810.5 (0–1.5)1011.0 (0–2.0)0.29<0.0001
Group 3 (HDA-MiDA)
 cJADAS10718.4 (5.0–12.7)851.5 (0.2–4.0)1131.0 (0–3.0)<0.00010.33
 Active joint count1193.0 (2.0–5.0)1150 (0–1)1190 (0–0)<0.00010.0004
 PaGA762.2 (1.0–4.3)890.4 (0–1.9)1150.5 (0–2.0)<0.0001<0.0001
 PhGA722.4 (1.0–4.2)860.3 (0–1.3)1160 (0–0.5)<0.00010.58
Group 4 (HDA-HDA)
 cJADAS102613.8 (6.6–19.0)277.8 (2.6–15.5)3510.0 (6.5–14.0)0.080.46
 Active joint count364.0 (2.5–10.0)362.5 (0–6.0)362.0 (0–3.5)0.010.38
 PaGA262.8 (1.0–6.2)281.9 (0.5–5.1)354.0 (2.0–7.5)0.99<0.0001
 PhGA274.4 (2.0–5.1)292.3 (0.8–5.0)363.0 (1.0–4.5)0.39<0.0001
  • Disease activity trajectory groups from baseline to 18-year follow-up.

  • Values are median IQR and total numbers.

  • *P value in the first column is for the difference between baseline and 8-year follow-up. P value in the second column is for the difference between 8-year and 18-year follow-up.

  • cJADAS10, clinical Juvenile Arthritis Disease Activity score (0–30); HDA, high disease activity; ID, inactive disease; MDA, moderate disease activity; MiDA, minimal disease activity; PaGA, patient global assessment of disease impact on well-being (0–10); PhGA, physician’s global assessment of disease activity (0–10).