Table 2

The parameters of ILD in patients with IIM with elevated RDW and normal RDW values

Elevated RDW (n=81)Normal RDW (n=238)P value
PaO2/FiO2 (n=295)346±74380±73<0.001
FVC% (n=286)69±1678±21<0.001
DLco% (n=286)52±1361±18<0.001
HRCT patterns, n (%)<0.001
 OP (n=127)47 (58)80 (33.6)
 NSIP (n=133)18 (22.2)115 (48.3)
 NSIP+OP (n=31)11 (13.6)20 (8.4)
 UIP (n=9)0 (0)9 (3.8)
MSA, n (%)0.047
 Anti-MDA5 (n=74)24 (29.6)50 (21)0.068
 Anti-ARS (n=127)36 (44.4)91 (38.2)0.3
 Others (n=118)21 (25.9)97 (40.7)0.017
RP-ILD, n (%)52 (64.2)72 (30.2)<0.001
  • Continuous data are presented as mean (M)±SEM or medians (IQR). Binary data are presented as n (%).

  • ARS, aminoacyl tRNA synthetase; DLco, carbon monoxide diffusion capacity; FVC, forced vital capacity; HRCT, high-resolution CT; IIM, idiopathic inflammatory myopathy; ILD, interstitial lung disease; MDA5, melanoma differentiation-associated gene 5; MSA, myositis-specific autoantibodies; NSIP, non-specific interstitial pneumonia; OP, organising pneumonia; PaO2/FiO2, ratio of partial pressure of oxygen in arterial blood to the fraction of inspiratory oxygen concentration; RDW, red cell distribution width; RP-ILD, rapidly progressive ILD; UIP, usual interstitial pneumonia.