At baseline | 1st year | 2nd year | 3rd year | |
mTSS, n | 476 | 476 | 394 | 314 |
mTSS, median (IQR) | 0 (0–2) | 0 (0–3) | 0 (0–5) | 0 (0–6) |
JSN, median (IQR) | 0 (0–1) | 0 (0–2) | 0 (0–2) | 0 (0–3) |
Erosion score, median (IQR) | 0 (0–1) | 0 (0–2) | 0 (0–2) | 0 (0–2) |
Estimated mTSS*, mean (95% CI) | 6.9 (1.2–11.6) | 7.4 (1.7–12.1) | 7.9 (2.2–12.6) | 8.4 (2.7–13.0) |
Current radiographic lesion†, % (n) | 30 (143) | 32 (150) | 35 (138) | 38 (119) |
Current erosive lesion†, % (n) | 25 (122) | 28 (124) | 30 (117) | 32 (101) |
Current JSN†, % (n) | 28 (135) | 31 (137) | 33 (130) | 36 (112) |
*Estimated marginal mean mTSS values by reaching to run a linear mixed model (adjusted for age).
†mTSS >0, erosion score >0, JSN>0.
JSN, joint space narrowing; mTSS, modified Total Sharp/van der Heijde Score; n, number of case.