Multivariable Cox regression model of the association between arrhythmia and mortality in patients with systemic sclerosis (SSc) comprising sex (women as reference), index age (as a continuous variable) and baseline comorbidities, in addition to pulmonary arterial hypertension as time-varying covariate
| Arrhythmia | SSc population (n=1393) | ||
| Patients with incident arrhythmia (n) | Arrhythmia prior to death (n) | HR (95% CI) | |
| Arrhythmia overall | 150 | 74 | 2.2 (1.6 to 3.0) |
| Conduction disorders | 19 | 10 | 1.1 (0.6 to 2.3) |
| Atrial fibrillation and flutter | 108 | 60 | 2.2 (1.6 to 3.1) |
| Cardiac arrest and ventricular arrhythmia | 21 | 15 | 5.7 (2.5 to 13.1) |
| PSVT | 12 | 2 | 1.5 (0.4 to 6.3) |
| Other | 25 | 3 | 1.1 (0.4 to 3.6) |
Arrhythmia was treated as time-varying covariate in the model.
Bold font indicates statistically significant values.
PSVT, paroxysmal supraventricular tachycardia.