Table 5

Logistic regression on active disease and remission off medication as dependent variables at 18-year follow-up (FU)

	B	SE	Wald	df	Sig	Exp(B)	95% CI
Active disease
IL-1β	0.903	0.746	1.464	1	0.226	2.467	0.57 to 10.65
IL-6	−0.098	0.642	0.023	1	0.879	0.907	0.26 to 3.19
MMP-3	0.51	0.612	0.695	1	0.404	1.665	0.50 to 5.52
IL-12	0.015	0.510	0.001	1	0.976	1.015	0.37 to 2.76
IL-13	0.211	0.798	0.070	1	0.791	1.235	0.26 to 5.91
S100A9	1.106	0.472	5.480	1	0.019	3.022	1.20 to 7.63
S100A12	−0.165	0.560	0.087	1	0.768	0.848	0.28 to 2.54
ESR log	0.537	0.624	0.741	1	0.389	1.711	0.50 to 5.82
Active joints log	0.566	1.157	0.239	1	0.625	1.761	0.18 to 17.00
Cumulative joints log	0.186	0.984	0.036	1	0.850	1.205	0.18 to 8.29
Remission off medication
IL-1β	−0.515	0.497	1.071	1	0.301	0.598	0.23 to 1.58
MMP-3	−0.531	0.372	2.042	1	0.153	0.588	0.28 to 1.22
IL-12	−0.151	0.377	0.161	1	0.689	0.860	0.41 to 1.80
S100A9	−0.313	0.330	0.901	1	0.342	0.731	0.38 to 1.40
Cumulative joints log	−0.582	0.378	2.369	1	0.124	0.559	0.27 to 1.17

For the goodness of fit, the ‘omnibus tests of model coefficients’ (‘Active disease’: χ²=27.22, p=0.002; ‘Remission off medication’: χ²=14.029, p=0.015) and the Hosmer and Lemeshow test (‘Active disease’: χ²=5.597, p=0.692; ‘Remission off medication’: χ²=6.332, p=0.610) both indicated support for the model.
Bold values indicate a unique statistically contribution to the model.
ESR, erythrocyte sedimentation rate; IL, interleukin; log, logarithm; MMP-3, matrix metalloproteinase 3.