Table 1

Systemic Lupus international Collaborating Clinics Frailty Index health deficits

Health deficitScoring system
DiabetesNo=0, yes=1
MalignancyNo=0, yes=1
Coronary artery diseaseNo=0, yes=1
Congestive heart failureNo=0, yes=1
Peripheral vascular diseaseNo=0, yes=1
Cerebrovascular diseaseNo=0, yes=1
Chronic kidney diseaseNone=0, stage 1=0.2, stage 2=0.4, stage 3=0.6, stage 4=0.8, stage 5=1
Deforming or erosive arthritisNo=0, yes=1
Venous thromboembolismNo=0, yes=1
Pulmonary diseaseNo=0, yes=1
Gastrointestinal diseaseNo=0, yes=1
Osteoporosis/avascular necrosisNo=0, yes=1
Ocular manifestations related to SLENo=0, yes=1
SLE myocarditis/endocarditisNo=0, yes=1
Cognitive impairmentNo=0, yes=1
Seizures/seizure disordersNo=0, yes=1
Altered mental statusNo=0, yes=1
NeuropathyNo=0, yes=1
Other neuropsychiatric manifestationsNo=0, yes=1
Active nephritisNo=0, yes=1
Active nephrotic syndromeNo=0, yes=1
Active serositisNo=0, yes=1
Active inflammatory arthritisNo=0, yes=1
Active inflammatory rashNo=0, yes=1
Active mucosal ulcersNo=0, yes=1
AlopeciaNo=0, yes (acute)=0.5, yes (chronic)=1
Active vasculitisNo=0, yes=1
Haematological disordersNo=0, yes=1
Immunological disordersNo=0, yes=1
Complement levelsNormal/high=0, low and negative dsDNA=0.5, low and positive dsDNA=1
Sjogren’s syndromeNo=0, yes=1
HypothyroidismNo=0, yes=1
HypertensionNo=0, yes=1
Body mass index (BMI)BMI 18.5–24.9 kg/m2=0, BMI 25–29.9 kg/m2=0.5, BMI>30 kg/m2=1
Mood disorderNo=0, yes=1
Anxiety disorderNo=0, yes=1
Headache disorderNo=0, yes=1
Self-rated healthExcellent=0, very good=0.25, good=0.5, fail=0.75, Poor=1
Self-reported deterioration in healthBetter or same=0, somewhat worse=0.5, much worse=1
Vigorous activitiesNot limited at all=0, somewhat limited=0.5, limited a lot=1
Moderate activitiesNot limited at all=0, somewhat limited=0.5, limited a lot=1
Lifting/carrying groceriesNot limited at all=0, somewhat limited=0.5, limited a lot=1
Climbing stairsNot limited at all=0, somewhat limited=0.5, limited a lot=1
Bending, kneeling or stoopingNot limited at all=0, somewhat limited=0.5, limited a lot=1
Walking 100 metresNot limited at all=0, somewhat limited=0.5, limited a lot=1
Bathing or dressingNot limited at all=0, somewhat limited=0.5, limited a lot=1
Self-rated fatigueNone=0, a little=0.2, some=0.4, moderate=0.6, most=0.8, always=1
Self-rated painNone=0, very mild=0.2, mild=0.4, moderate=0.6, severe=0.8, very severe=1
  • dsDNA, double strand DNA; SLE, systemic lupus erythematosus.