Variables | OR | 95% CI | P value |
Age | 1.14 | 1.09 to 1.20 | 0.000 |
Gender | 0.51 | 0.18 to 1.42 | 0.203 |
Disease duration | 1.06 | 1.01 to 1.11 | 0.007 |
SLEDAI-2K | 0.97 | 0.87 to 1.08 | 0.663 |
SDI | 1.33 | 0.86 to 2.05 | 0.191 |
LLDAS | 0.87 | 0.40 to 1.91 | 0.741 |
Antiphospholipid syndrome | 1.23 | 0.48 to 3.09 | 0.657 |
Double or triple aPL positivity | 1.02 | 0.45 to 2.30 | 0.961 |
Cumulative prednisone dose | 1.00 | 0.99 to 1.00 | 0.186 |
Hydroxychloroquine use | 0.86 | 0.32 to 2.30 | 0.779 |
Immunosuppressives use | 1.13 | 0.54 to 2.38 | 0.736 |
Systolic blood pressure | 1.01 | 0.99 to 1.03 | 0.121 |
Smoking, pack-years | 1.06 | 1.03 to 1.09 | 0.000 |
Smoking current | 1.70 | 1.06 to 2.72 | 0.026 |
Family history of premature CAD | 0.22 | 0.02 to 1.75 | 0.155 |
Total cholesterol | 1.00 | 0.99 to 1.01 | 0.454 |
HDL | 0.97 | 0.95 to 0.99 | 0.023 |
LDL | 1.00 | 0.99 to 1.01 | 0.128 |
Triglycerides | 1.00 | 1.00 to 1.01 | 0.024 |
BMI | 1.00 | 0.98 to 1.02 | 0.704 |
Hypertension | 2.79 | 1.32 to 5.88 | 0.007 |
Dyslipidaemia | 3.00 | 1.35 to 6.66 | 0.007 |
Antihypertensives | 0.97 | 0.89 to 1.06 | 0.563 |
Statins | 2.14 | 0.81 to 5.65 | 0.122 |
Antiplatelets | 1.44 | 0.65 to 3.15 | 0.359 |
SCORE | 1.99 | 1.61 to 2.45 | 0.000 |
Cardiovascular risk class | 10.82 | 4.88 to 23.96 | 0.000 |
SLICC-FI score* | 1.54 | 1.16 to 2.01 | 0.002 |
Bold values denote statistical significance at the p < 0.05 level.
*Per 0.05 increase.
aPL, antiphospholipid antibodies; BMI, body mass index; CAD, coronary artery disease; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LLDAS, lupus low disease activity state; SCORE, Systematic COronary Risk Evaluation prediction of 10-year fatal cardiovascular disease; SDI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index; SLICC-FI, Systemic Lupus International Collaborating Clinics-Frailty Index.