Table 6

Univariate analysis of the association between femoral plaque presence and several disease-related and traditional cardiovascular risk factors in patients with systemic lupus erythematosus (n=202)

VariablesOR95% CIP value
Age1.141.09 to 1.200.000
Gender0.510.18 to 1.420.203
Disease duration1.061.01 to 1.110.007
SLEDAI-2K0.970.87 to 1.080.663
SDI1.330.86 to 2.050.191
LLDAS0.870.40 to 1.910.741
Antiphospholipid syndrome1.230.48 to 3.090.657
Double or triple aPL positivity1.020.45 to 2.300.961
Cumulative prednisone dose1.000.99 to 1.000.186
Hydroxychloroquine use0.860.32 to 2.300.779
Immunosuppressives use1.130.54 to 2.380.736
Systolic blood pressure1.010.99 to 1.030.121
Smoking, pack-years1.061.03 to 1.090.000
Smoking current1.701.06 to 2.720.026
Family history of premature CAD0.220.02 to 1.750.155
Total cholesterol1.000.99 to 1.010.454
HDL0.970.95 to 0.990.023
LDL1.000.99 to 1.010.128
Triglycerides1.001.00 to 1.010.024
BMI1.000.98 to 1.020.704
Hypertension2.791.32 to 5.880.007
Dyslipidaemia3.001.35 to 6.660.007
Antihypertensives0.970.89 to 1.060.563
Statins2.140.81 to 5.650.122
Antiplatelets1.440.65 to 3.150.359
SCORE1.991.61 to 2.450.000
Cardiovascular risk class10.824.88 to 23.960.000
SLICC-FI score*1.541.16 to 2.010.002
  • Bold values denote statistical significance at the p < 0.05 level.

  • *Per 0.05 increase.

  • aPL, antiphospholipid antibodies; BMI, body mass index; CAD, coronary artery disease; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LLDAS, lupus low disease activity state; SCORE, Systematic COronary Risk Evaluation prediction of 10-year fatal cardiovascular disease; SDI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index; SLICC-FI, Systemic Lupus International Collaborating Clinics-Frailty Index.