RA | AS | PsA | SLE | SjD | iRMD total | OA | N missing | |
Subjective memory complaints | ||||||||
Memory worse, % (n)* | 31 (652) | 24 (129) | 25 (121) | 32 (45) | 33 (29) | 29 (867) | 27 (6119) | 16 283 |
Memory worse with concern about it, % (n)* | 22 (455) | 15 (77) | 18 (82) | 21 (31) | 17 (15) | 20 (580) | 17 (3829) | 19 698 |
Memory worse with contact to a physician, % (n)* | 13 (268) | 8.8 (46) | 9.0 (43) | 14 (20) | 15 (13) | 12 (347) | 9.6 (2139) | 19 719 |
Episodic memory domain | ||||||||
Word list recall, immediate, mean±SD, range 1–12, (n) | 6.5±1.8 (1942) | 6.6±1.7 (495) | 6.7±1.8 (456) | 6.9±1.8 (132) | 6.6±1.5 (80) | 6.5±1.7 (2789) | 6.5±1.7 (21 349) | 1200 |
Word list recall, repeat, mean±SD, range 1–12 (n) | 9.2±1.8 (1933) | 9.3±1.8 (494) | 9.3±1.8 (453) | 9.6±1.8 (130) | 9.4±1.6 (79) | 9.3±1.8 (2773) | 9.2±1.8 (21 204) | 1250 |
Word list recall, delayed, mean±SD, range 1–12 (n) | 7.8±2.3 (1933) | 7.9±2.4 (494) | 7.9±2.4 (453) | 8.4±2.3 (130) | 7.9±2.1 (79) | 7.8±2.4 (2773) | 7.7±2.4 (21 204) | 1421 |
Executive function domain | ||||||||
Semantic fluency (animal names), mean±SD, range 1–79, (n) | 24±6.8 (1948) | 25±7.1 (496) | 25±6.7 (459) | 25±6.9 (132) | 26±6.9 (80) | 25±6.9 (2798) | 25±6.8 (21 403) | 1100 |
Stroop task 1 (colour naming), mean±SD, range 11–422, (n) | 22±5.1 (1942) | 22±4.3 (494) | 22±4.8 (456) | 22±4.7 (131) | 21±3.4 (80) | 22±5.0 (2788) | 22±4.7 (21 335) | 1610 |
Stroop task 2 (incongruent condition), mean±SD, range 11–422, (n) | 46±14 (1942) | 44±14 (494) | 46±15 (456) | 43±14 (131) | 44±13 (80) | 45±14 (2788) | 45±15 (21 335) | 1622 |
Stroop effect (incongruent – colour naming), mean±SD, −250–360 | 24±12 | 22±12 | 24±13 | 21±11 | 23±11 | 23±12 | 23±13 | 1626 |
Digit span backwards, mean±SD, range 2–9, (n) | 4.5±1.2 (1931) | 4.6±1.2 (495) | 4.6±1.2 (454) | 4.7±1.4 (131) | 4.7±1.2 (79) | 4.6±1.2 (2777) | 4.6±1.2 (21 273) | 1321 |
Number series task only Level 2, (n) | 502±21 (372) | 500±22 (107) | 505±19 (89) | 502±22 (18) | 507±24 (16) | 502±21 (538) | 502±21 (4110) | 22 140 |
NAKO, based on NAKO data freeze 100 000; application NAKO-603.
*Only for ≥45 year olds.
AS, ankylosing spondylitis; iRMD, inflammatory rheumatic disease; MDD, major depressive disorder; MINI, Mini-International Neuropsychiatric Interview; NAKO, German National Cohort; OA, osteoarthritis; PsA, psoriatic arthritis; RA, rheumatoid arthritis; SjD, Sjögren’s disease; SLE, systemic lupus erythematosus.