Patients’ characteristics according to database
| AIDnet | JIRcohort | P value | |
| n | 455 | 292 | |
| Females | 215 (47) | 145 (50) | 0.59 |
| Mutational status | |||
| Homozygous | 132 (34) | 101 (37) | <0.001 |
| Compound heterozygous | 94 (25) | 107 (39) | |
| Heterozygous | 157 (41) | 67 (24) | |
| Class III | 72 (29) | 17 (6) | |
| Colchicine stop ever in heterozygous patients | 36 (23) | 16 (24) | 1 |
| Median number of visits | 6 (3–10) | 3 (2–5) | <0.001 |
| Age at colchicine stop in heterozygous patients (years) | 8.08 (5.25–17.17) | 10.41 (9.6–16.71) | 0.08 |
| Total time under colchicine in heterozygous patients (years) | 1.17 (0.9–5) | 6.54 (4.58–12.5) | 0.006 |
| Number of patients with ≥1 measurements | |||
| S100A8/A9 | 137 (60) | 20 (7) | <0.001 |
| S100A12 | 170 (37) | 2 (1) | <0.001 |
Values are number (%) for categorical variables or median (IQR) for continuous variables.
Bold values indicate p-value<0.05.