NSST long-term subtype stability. UKPSSR cohort: 274 patients classified at baseline and follow-up. ASSESS cohort: 237 patients classified at baseline and 60 months follow-up. The table shows the percentage of the entire cohort that retained subtype membership (overall stability) between baseline and final follow-up, along with the percentage of patients that retained subtype membership (subtype stability). The subtype most transitioned to by each subtype and the percentage of the baseline subtype that made this transition are also shown below.
| LSB | DDF | HSB | Overall stability | |||
| UKPSSR | Subtype membership retained | 51.28% | 60.71% | 55.56% | 70.42% | 59.9% |
| Most common transition at follow-up | DDF 23.07% | PDF 23.21% | DDF 20.37% | PDF 22.53% | ||
| ASSESS | Subtype membership retained | 41.02% | 37.93% | 65.59% | 67.74% | 57.4% |
| Most common transition at 5- year follow-up | PDF 32.07% | PDF 31.03% | HSB 22.58% | PDF 29.03% |
ASSESS, Assessment of Systemic Signs and Evolution of Sjögren’s Syndrome ; DDF, dryness dominant with fatigue; HSB, high symptom burden; LSB, low symptom burden; PDF, pain dominant with fatigue; UKPSSR, United Kingdom Primary Sjögren’s Syndrome Registry.