Table 3

Sensitivity to change for the ScleroID between baseline and follow-up (SRM)

PROM	SRM (improved)	SRM (worsened)	SRM (stable)
ScleroID
Raynaud score	−1.317	0.259	0.000
Hand function score	−0.855	0.403	−0.070
Pain score	−0.605	0.225	0.152
Fatigue score	−0.661	0.496	0.020
Upper GI score	0.231	−0.195	−0.097
Lower GI score	0.194	0.170	−0.134
Life choices score	0.210	0.177	−0.129
Body mobility score	0.000	0.279	−0.271
Dyspnoea score	0.422	0.277	0.013
Digital ulcers score	−0.249	0.526	−0.367
ScleroID total score	−0.634	0.483	−0.118
SF-36 Physical Component score	0.478	−0.352	0.261
SF-36 Mental Component score	0.567	0.138	0.120
HAQ-DI score	−0.441	−0.327	−0.187
SSc-HAQ score	−0.511	−0.244	−0.112
EQ-5D score	0.988	0.133	0.010

Thresholds: SRM <0.2–0.5 low, 0.5–0.8 moderate, >0.8 large responsiveness, respectively.20
EQ-5D, EuroQol-5 Dimensional Questionnaire; GI, gastrointestinal tract; HAQ-DI, Health Assessment Questionnaire Disability Index; PROMs, patient-reported outcome measures; ScleroID, Systemic Sclerosis Impact of Disease; SF-36, Short Form (36) Health Survey; SRM, standardised response mean; SSc, systemic sclerosis.