Skip to main content
SpringerLink
Log in

Cardiovascular manifestations of ankylosing spondylitis

  • Originals
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Summary

In a retrospective study, 40 patients with ankylosing spondylitis were assessed for extraspinal manifestations. Cardiovascular complications were found in 17 patients (42.5%)∶5(12.5%) had aortic insufficiency, 3 (7.5%) had atrioventricular block and 5 (12.5%) had bundle branch block. Wolff-Parkinson-White syndrome was diagnosed in one case and short PR syndrome in another. Cardiovascular complications were more common in patients with longer disease duration. Ischemic heart disease was found in 17.5% of the cases and pulmonary fibrosis in 15%. Peripheral arthritis was found in 42.5% and its prevalence did not differ in patients with or without cardiac involvement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Kinsella, T.D., Johnson, L.G., Sutherland, R.I. Cardiovascular manifestations of ankylosing spondylitis. Canad Assoc J, 1974, 111, 1309–1311.

    CAS  Google Scholar 

  2. Graham, D.C., Smythe, H.A. The carditis and aoritis of ankylosing spondylitis. Bull Rheum Dis, 1958, 9, 171–174.

    CAS  PubMed  Google Scholar 

  3. Berstein, L., Broch, O.J. Cardiac complications in spondylarthritis ankylopoietica. Acta Med Scand, 1949, 135, 185–190.

    Google Scholar 

  4. Nitter-Hauge, S., Otterstad, J.E. Characteristics of atrioventricular conduction disturbances in ankylosing spondylitis (Mb Bechterew). Acta Med Scand 1981, 210, 197–200.

    CAS  PubMed  Google Scholar 

  5. Bennett, P.H., Burch, T.A. The epidemiological diagnosis of ankylosing spondylitis. Excerpta Medica International Congress Series, 1968, 148, 305–313.

    Google Scholar 

  6. Hecht, H.H., Kossman, C.E., Childers, R.W., Langendorf, R., Lev, M., Rosen, K.M., Pruitt, R.D., Truex, R.C., Uhley, H.N., Watt, T.B. Atrioventricular and intraventricular conduction. Revised nomenclature and concepts. Am J Cardiol 1973, 31, 232–244.

    Article  CAS  PubMed  Google Scholar 

  7. Robles de Medina, E.O., Bernard, R., Coumel, P., Damato, A.N., Fisch, C., Krikler, D., Mauzur, N.A., Meijler, F.L., Mogenson, L., Moret, A., Pisa, Z., Wellens, H.J. Definition of terms related to cardiac rhythm. Eur J Cardiol, 1978, 8, 127–144.

    CAS  PubMed  Google Scholar 

  8. Kinsella, T.D., MacDonald, F.R., Johnson, L.G. Ankylosing spondylitis: A late re-evaluation of 92 cases. Can Med Assoc J 1966, 95, 1–9.

    CAS  PubMed  Google Scholar 

  9. Ogryzlo, M.A., Rosen, P.S. Ankylosing (Marie-Strumpell) spondylitis. Postgrad Med, 1969, 45, 182–188.

    CAS  PubMed  Google Scholar 

  10. Hart, F.D. Ankylosing spondylitis. Lancet 1968, 2, 1340–1344.

    CAS  PubMed  Google Scholar 

  11. Calabro, J.J., Maltz, B.A. Ankylosing spondylitis. N Eng J Med 1970, 282, 606–610.

    CAS  Google Scholar 

  12. Bulkley, B.H., Roberts, W.C. Ankylosing spondylitis and aortic regurgitation: Description of the characteristic cardio-vascular lesion from study of eight necropsy patients. Circulation 1973, 48, 1014–1027.

    CAS  PubMed  Google Scholar 

  13. Roberts, W.C., Holingsworth, J.F., Bulkley, B.H., Jaffe, R.B., Epstein, S.E., Stinson, E.B. Combined mitral and aortic regurgitation in ankylosing spondylitis: Angiographic and anatomic features. Am J Med 1974, 56, 237–243.

    Article  CAS  PubMed  Google Scholar 

  14. Bachmann, F., Hartl, W., Veress, M., Frind, W. Kardiovaskulare complikationen bei spondylitis ankylosans (Morbus Bechterew). Med Welt 1976, 27, 2149–2150.

    CAS  PubMed  Google Scholar 

  15. Demoulin, J.C., Lespagnard, J., Bertholet, M., Soumagne, D. Acute fulminant aortic regurgitation in ankylosing spondylitis. Am Heart J 1983, 105, 859–861.

    Article  CAS  PubMed  Google Scholar 

  16. Pelkonen, P., Byring, R., Pesonen, E., Leijala, M., Haapasaari, J. Rapidly progressive aortic incompetence in juvenile ankylosing spondylitis. Arthritis Rheum 1984, 27, 698–700.

    CAS  PubMed  Google Scholar 

  17. Tucker, C.R., Fowler, R.E., Calin, A., Popp, R.L. Aortitis in ankylosing spondylitis: Early detection of aortic root abnormalities with two dimensional echocardiography. Am J Cardiol 1982, 49, 680–686.

    Article  CAS  PubMed  Google Scholar 

  18. Stewart, S.R., Robbins, D.L., Castles, J.J. Acute fulminant aortic and mitral insufficiency in ankylosing spondylitis. N Engl J Med 1978, 299, 1448–1449.

    CAS  PubMed  Google Scholar 

  19. Hull, R.S., Asherson, R.A., Rennie, J.A.N. Ankylosing spondylitis and an aortic arch syndrome. Br Heart J 1984, 51, 663–665.

    CAS  PubMed  Google Scholar 

  20. Hiss, R.G., Lamb, L.E. Electrocardiographic finding in 122,043 individuals. Circulation 1982, 25, 947–961.

    Google Scholar 

  21. Suter, L., Steiger, U. Aortoval vulopathie and cardiale Storungen bei spondylitis ankylopoetica. Cardiologia 1962, 41, 15–30.

    CAS  PubMed  Google Scholar 

  22. Bergfeldt, L., Edhag, O., Vallin, H. Cardiac conduction disturbances, an underestimated manifestation in ankylosing spondylitis. Acta Med Scand 1982, 212, 217–223.

    CAS  PubMed  Google Scholar 

  23. Bottinger, L.E., Edhag, O. Heart block in ankylosing spondylitis and uropolyarthritis. Br Heart J 1972, 34, 487–492.

    Google Scholar 

  24. Liu, S.M., Alexander, C.S. Complete heart block and aortic insufficiency in rheumatoid spondylitis. Am J Cardiol 1969, 23, 888–892.

    Article  CAS  PubMed  Google Scholar 

  25. Jensen, G., Sigurd, B., Meibom., Sande, E. Adams-Stokes syndrome caused by paroxysmal third-degree atrioventricular block. Br Heart J 1973, 35, 516–520.

    CAS  PubMed  Google Scholar 

  26. Edhag, O., Rosenqvist, M. Heart rhythm during permanent cardiac pacing. Br Heart J 1979, 42, 182–185.

    CAS  PubMed  Google Scholar 

  27. Rytland, D.A., Stinson, E., Kelly, J.J. Remission and recovery from chronic, established complete heart block. Am Heart J 1976, 91, 645–652.

    Google Scholar 

  28. Bergfeldt, L., Edhag, O., Vedin, L., Vallin, H. Ankylosing spondylitis: An important cause of severe disturbances of the cardiac conduction system. Prevalence among 223 pacemaker-treated men. Am J Med 1982, 73, 187–191.

    Article  CAS  PubMed  Google Scholar 

  29. James, T.N. Rheumatoid arthritis and ankylosing spondylitis. De subitaneis mortibus. Clinicopathologic correlations. Circulation 1977, 55, 669–677.

    CAS  PubMed  Google Scholar 

  30. Resnick, D. Pattern of peripheral joint disease in ankylosing spondylitis. Radiology 1974, 110, 523–532.

    CAS  PubMed  Google Scholar 

  31. Engleman, E.G., Engelman, E.P. Ankylosing spondylitis-recent advances in diagnosis and treatment. Med Clin North Am 1977, 61, 347–364.

    CAS  PubMed  Google Scholar 

  32. Cruickshand, B. Pathology of ankylosing spondylitis. Clin Orthop 1971, 74, 43–58.

    Google Scholar 

  33. Godeau, P., Bletry, O., Herreman, G. Troubles di conduction intracardiaques au cours de la spondylarthrite ankylosante. Ann Med Interne 1976, 127, 203–214.

    CAS  Google Scholar 

  34. Davis, D. Ankylosing spondylitis and lung fibrosis. Q J Med 1972, 41, 395–417.

    Google Scholar 

  35. Vale, J.A., Pickering, J.G., Scott, G.W. Ankylosing spondylitis and upper lobe fibrosis and cavitation. Guys Hosp Rep 1974, 123, 97–119.

    CAS  PubMed  Google Scholar 

  36. Feltelius, N., Hendenstrom, H., Hillerdal, G., Hallgren, R. Pulmonary involvement in ankylosing spondylitis. Ann Rheum Dis 1986, 45, 736–740.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Rheumatology Unit and Department of Medicine “A”, Soroka Medical Center and Faculty of Health Sciences, Ben Gurion University of the Negev, P.O.B. 151, Beer Sheva, Israel

    S. Sukenik, A. Pras, D. Buskila, A. Katz, Y. Snir & J. Horowitz

Authors
  1. S. Sukenik
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Pras
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. Buskila
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Katz
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Y. Snir
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Horowitz
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sukenik, S., Pras, A., Buskila, D. et al. Cardiovascular manifestations of ankylosing spondylitis. Clin Rheumatol 6, 588–592 (1987). https://doi.org/10.1007/BF02330598

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02330598

Key words

Search

Navigation