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A new superfamily of cell surface proteins related to the nerve growth factor receptor

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Abstract

In this article Susan Mallett and Neil Barclay discuss the molecular and functional features of a new superfamily of membrane proteins defined by the presence of cysteine-rich motifs originally identified in the low-affinity nerve growth factor receptor. This superfamily includes two lymphocyte proteins of unknown function and two receptors for tumor necrosis factor.

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    Susan Mallett was supported by a Medical Research Council studentship.

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