A possible role of sex in determining distribution of lesions in Takayasu Arteritis
Section snippets
Methods and materials
One hundred and twelve patients of TA proved angiographically were included in the present study. All the patients underwent a detailed clinical, biochemical and radiological examination. The clinical examination included recording of blood pressure in all the limbs, auscultation for various bruits, presence or absence of peripheral pulses and a fundus examination. Details of this group have been reported earlier 4, 5.
Results
Of 112 of these patients with TA, there were 89 females and 43 males with a female to male ratio of 1.6:1. Their ages ranged from 5 to 55 years with a mean of 27.8±9.4 years.
The common mode of presentation in our patients included hypertension (52.7%), headache (45.5%), dyspnea (25.9%) and syncope (25.9%). Other features at the time of presentation are shown in Table 1 and Table 2.
The common findings among female patients with TA included hypertension (68%), anaemia (34.8%) and vascular bruit
Discussion
The female to male ratio amongst patients with TA varies from 9.4:1 to 1.6:1 in various countries including Japan, China, Thailand, Korea, Mexico, Israel, Singapore and India 6, 7, 9, 10, 11, 13, 14, 15, 16. Japan, Korea, USA and Mexico have predominant female population amongst patients of TA while India, Thailand and China do not show that female predominance (Table 5).
It is interesting to compare Indian female patients with Japanese patients of TA (Female:male ratio 9.4:1) (Table 6). It
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