Original articlesCardiovascularSurgical Treatment of Ascending Aortic Aneurysms in Patients With Giant Cell Aortitis
Section snippets
Patients
Thirty-seven patients with an aneurysm involving the ascending aorta caused by giant cell aortitis underwent surgery at the Mayo Clinic, Rochester, MN, between January 1995 and December 2002. A retrospective review of our surgical database and patient medical records was performed. Follow-up information was obtained by questionnaire or telephone calls to assess current status of health, medications, and any significant medical events. The primary indication for surgery in all 37 patients was a
Results
Demographics, presenting symptoms, and significant comorbidities are listed in Table 1. Seventeen (45.9%) patients were in New York Heart Association class III or IV. Nineteen (51%) had greater than grade II aortic regurgitation. Moderate mitral and tricuspid regurgitation was documented in 3 patients each. Two patients had significant aortic stenosis. Three patients had a prior thoracoabdominal aneurysm repair, of which 2 patients underwent emergent surgery because of a leaking aneurysm. One
Comment
Giant cell arteritis can effect the entire vascular tree. Lie [10] has documented that in 72 patients with extracranial disease, the ascending aorta and aortic arch were involved in 39% of cases, the subclavian and axillary arteries in 28%, and the femoropopliteal arteries in 18%. Twenty-five percent had associated temporal arteritis. This ratio was similar in our series. Whereas only 8% of patients had biopsy-proven temporal arteritis in the past, a total of 10 (27%) patients had clinical
References (16)
- et al.
Aortic dissection in giant-cell arteritis
Semin Arthritis Rheum
(1995) Aortic and extracranial large vessel giant cell arteritis: a review of 72 cases with histopathologic documentation
Semin Arthritis Rheum
(1995)Giant cell arteritis and Takayasu aortitis: morphologic, pathogenetic and etiologic factors
Int J Cardiol
(2000)- et al.
Giant arteritis presenting with annuloaortic ectasia
Chest
(2002) Diseases of the arteriesOn a peculiar form of thrombotic arteritis of the aged which is sometimes productive of gangrene
Arch Surg (Lond)
(1890)- et al.
An undescribed form of arteritis of the temporal vessels
Mayo Clin Proc
(1932) Temporal arteritis in a large necropsy series
Ann Rheum Dis
(1971)- et al.
Trends in incidence and clinical presentation of temporal arteritis in Olmstead County, Minnesota, 1950–1985
Arthritis Rheum
(1988)
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