Uveitis in childhood: an Italian clinical and epidemiological study

Ocul Immunol Inflamm. 2009 Jul-Aug;17(4):238-42. doi: 10.1080/09273940802702561.

Abstract

Purpose: To investigate demographics, causes, features, and visual outcomes of pediatric uveitis.

Methods: Retrospective cohort study including 257 patients younger than 16 years.

Results: Mean age at onset of uveitis was 8.54 +/- 3.98 years; 54.5% of the patients were girls. Anterior uveitis occurred in 47.8%, intermediate in 19.4%, posterior in 24.9%, panuveitis in 7.8%. Ocular involvement was bilateral in 67.8%. Infectious uveitis represented 31% of all cases. Causes of severe visual loss were cataract, macular scars, macular edema/maculopathy, and secondary glaucoma. At follow-up 79.3% of eyes maintained a visual acuity between 20/32 and 20/20.

Conclusions: Uveitis is rarer in children than in adults. Patients with anterior uveitis comprised the largest group. Posterior uveitis in the pediatric population has a lower incidence than some decades ago. Visual prognosis of pediatric uveitis is improving, owing to an earlier diagnosis and a correct treatment.

MeSH terms

  • Adolescent
  • Age of Onset
  • Cataract
  • Child
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Glaucoma / complications
  • Humans
  • Incidence
  • Infections
  • Italy / epidemiology
  • Macula Lutea
  • Male
  • Prognosis
  • Retinal Diseases / complications
  • Retrospective Studies
  • Sex Distribution
  • Uveitis / epidemiology*
  • Uveitis / etiology
  • Uveitis / microbiology
  • Uveitis / physiopathology*
  • Vision Disorders / etiology
  • Visual Acuity