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Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response.
Hamkour S, van der Heijden EH, Lopes AP, Blokland SLM, Bekker CPJ, Van Helden-Meeuwsen CG, Versnel MA, Kruize AA, Radstake TR, Leavis HL, Hillen MR, van Roon JA. Hamkour S, et al. Among authors: blokland slm. RMD Open. 2023 Aug;9(3):e002979. doi: 10.1136/rmdopen-2023-002979. RMD Open. 2023. PMID: 37532471 Free PMC article.
The Transcriptomic Profile of Monocytes from Patients With Sjögren's Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators.
Lopes AP, Bekker CPJ, Hillen MR, Blokland SLM, Hinrichs AC, Pandit A, Kruize AA, Radstake TRDJ, van Roon JAG. Lopes AP, et al. Among authors: blokland slm. Front Immunol. 2021 Aug 3;12:701656. doi: 10.3389/fimmu.2021.701656. eCollection 2021. Front Immunol. 2021. PMID: 34413853 Free PMC article.
Autoantibodies to Cytosolic 5'-Nucleotidase 1A in Primary Sjögren's Syndrome and Systemic Lupus Erythematosus.
Rietveld A, van den Hoogen LL, Bizzaro N, Blokland SLM, Dähnrich C, Gottenberg JE, Houen G, Johannsen N, Mandl T, Meyer A, Nielsen CT, Olsson P, van Roon J, Schlumberger W, van Engelen BGM, Saris CGJ, Pruijn GJM. Rietveld A, et al. Among authors: blokland slm. Front Immunol. 2018 Jun 5;9:1200. doi: 10.3389/fimmu.2018.01200. eCollection 2018. Front Immunol. 2018. PMID: 29922285 Free PMC article.
Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production.
Hillen MR, Pandit A, Blokland SLM, Hartgring SAY, Bekker CPJ, van der Heijden EHM, Servaas NH, Rossato M, Kruize AA, van Roon JAG, Radstake TRDJ. Hillen MR, et al. Among authors: blokland slm. Front Immunol. 2019 Sep 4;10:2096. doi: 10.3389/fimmu.2019.02096. eCollection 2019. Front Immunol. 2019. PMID: 31552042 Free PMC article.
Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren's syndrome is associated with B cell hyperactivity and type I interferon activity.
Hillen MR, Urso K, Koppe E, Lopes AP, Blokland SLM, Pandit A, Slocombe T, van Maurik A, van Roon JAG, Radstake TRDJ. Hillen MR, et al. Among authors: blokland slm. RMD Open. 2020 Jun;6(2):e001184. doi: 10.1136/rmdopen-2020-001184. RMD Open. 2020. PMID: 32540951 Free PMC article. No abstract available.
23 results