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Page 1
Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes.
Gjefsen E, Gervin K, Bråten LCH, Goll GL, Aass HCD, Schistad EI, Wigemyr M, Pedersen LM, Skouen JS, Vigeland MD, Selmer KK, Storheim K, Zwart JA. Gjefsen E, et al. Among authors: wigemyr m. Osteoarthritis Cartilage. 2023 Apr;31(4):543-547. doi: 10.1016/j.joca.2023.01.001. Epub 2023 Jan 12. Osteoarthritis Cartilage. 2023. PMID: 36640896 Free article. Clinical Trial.
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement.
Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Kristoffersen PM, Vetti N, Wigemyr M, Bråten LCH, Gjefsen E, Schistad EI, Haugen AJ, Froholdt A, Skouen JS, Zwart JA, Storheim K, Pedersen LM, Lie BA; AIM Study Group. Vigeland MD, et al. Among authors: wigemyr m. Sci Rep. 2022 Jan 7;12(1):215. doi: 10.1038/s41598-021-04189-5. Sci Rep. 2022. PMID: 34997115 Free PMC article.
Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain.
Bråten LCH, Grøvle L, Wigemyr M, Wilhelmsen M, Gjefsen E, Espeland A, Haugen AJ, Skouen JS, Brox JI, Zwart JA, Storheim K, Ostelo RW, Grotle M. Bråten LCH, et al. Among authors: wigemyr m. J Clin Epidemiol. 2022 Nov;151:75-87. doi: 10.1016/j.jclinepi.2022.07.012. Epub 2022 Aug 1. J Clin Epidemiol. 2022. PMID: 35926821 Free article. Clinical Trial.
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes.
Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Zucknick M, Wigemyr M, Bråten LCH, Gjefsen E, Zwart JA, Storheim K, Pedersen LM, Selmer K, Lie BA, Gervin K, The Aim Study Group. Vigeland MD, et al. Among authors: wigemyr m. Antibiotics (Basel). 2023 Jul 21;12(7):1217. doi: 10.3390/antibiotics12071217. Antibiotics (Basel). 2023. PMID: 37508313 Free PMC article.
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study).
Bråten LCH, Gjefsen E, Gervin K, Pripp AH, Skouen JS, Schistad E, Pedersen LM, Wigemyr M, Selmer KK, Aass HCD, Goll G, Brox JI, Espeland A, Grøvle L, Zwart JA, Storheim K; AIM-study group. Bråten LCH, et al. Among authors: wigemyr m. J Pain Res. 2023 May 23;16:1713-1724. doi: 10.2147/JPR.S406079. eCollection 2023. J Pain Res. 2023. PMID: 37252109 Free PMC article. Clinical Trial.
Cost-utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study).
Grotle M, Bråten LC, Brox JI, Espeland A, Zolic-Karlsson Z, Munk Killingmo R, Tingulstad A, Grøvle L, Froholdt A, Kristoffersen PM, Wigemyr M, van Tulder MW, Storheim K, Zwart JA; AIM-study group. Grotle M, et al. Among authors: wigemyr m. BMJ Open. 2020 Jun 15;10(6):e035461. doi: 10.1136/bmjopen-2019-035461. BMJ Open. 2020. PMID: 32546490 Free PMC article. Clinical Trial.
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial.
Bråten LCH, Rolfsen MP, Espeland A, Wigemyr M, Aßmus J, Froholdt A, Haugen AJ, Marchand GH, Kristoffersen PM, Lutro O, Randen S, Wilhelmsen M, Winsvold BS, Kadar TI, Holmgard TE, Vigeland MD, Vetti N, Nygaard ØP, Lie BA, Hellum C, Anke A, Grotle M, Schistad EI, Skouen JS, Grøvle L, Brox JI, Zwart JA, Storheim K; AIM study group. Bråten LCH, et al. Among authors: wigemyr m. BMJ. 2019 Oct 16;367:l5654. doi: 10.1136/bmj.l5654. BMJ. 2019. PMID: 31619437 Free PMC article. Clinical Trial.
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial.
Gjefsen E, Bråten LCH, Goll GL, Wigemyr M, Bolstad N, Valberg M, Schistad EI, Marchand GH, Granviken F, Selmer KK, Froholdt A, Haugen AJ, Dagestad MH, Vetti N, Bakland G, Lie BA, Haavardsholm EA, Nilsen AT, Holmgard TE, Kadar TI, Kvien T, Skouen JS, Grøvle L, Brox JI, Espeland A, Storheim K, Zwart JA. Gjefsen E, et al. Among authors: wigemyr m. BMC Musculoskelet Disord. 2020 Oct 21;21(1):698. doi: 10.1186/s12891-020-03720-5. BMC Musculoskelet Disord. 2020. PMID: 33087100 Free PMC article.