Update on the pathogenesis and treatment of juvenile idiopathic arthritis

G Giancane, A Alongi, A Ravelli - Current opinion in …, 2017 - journals.lww.com
A great deal of work is being conducted to better define the molecular phenotype of the
individual subsets of JIA and to identify potential new targets for therapeutic interventions …

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study

A Consolaro, G Giancane, A Alongi… - The Lancet Child & …, 2019 - thelancet.com
Background To our knowledge, the characteristics and burden of childhood arthritis have
never been studied on a worldwide basis. We aimed to investigate, with a cross-sectional …

Definition and validation of the American College of Rheumatology 2021 juvenile arthritis disease activity score cutoffs for disease activity states in juvenile idiopathic …

C Trincianti, EHP Van Dijkhuizen… - Arthritis & …, 2021 - Wiley Online Library
Objective To develop and validate new Juvenile Arthritis Disease Activity Score 10
(JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive …

[HTML][HTML] Disease activity and damage in juvenile idiopathic arthritis: methotrexate era versus biologic era

G Giancane, V Muratore, V Marzetti, N Quilis… - Arthritis research & …, 2019 - Springer
Objective To compare the long-term disease state, in terms of activity and damage, of
children with juvenile idiopathic arthritis (JIA) who had their disease onset in methotrexate …

[PDF][PDF] Open issues in the assessment and management of pain in juvenile idiopathic arthritis

G Giancane, A Alongi, S Rosina… - Clin Exp …, 2017 - clinexprheumatol.org
Pain is the major symptom of children with juvenile idiopathic arthritis (JIA) and its reduction
is a key goal of treatment. It is widely agreed that assessment of pain is a fundamental …

Establishing an updated core domain set for studies in juvenile idiopathic arthritis: a report from the OMERACT 2018 JIA workshop

EM Morgan, JE Munro, J Horonjeff, B Horgan… - The Journal of …, 2019 - jrheum.org
Objective. The current Juvenile Idiopathic Arthritis (JIA) Core Set used in randomized
controlled trials (RCT) and longitudinal observational studies (LOS) was developed without …

Recent therapeutic advances in juvenile idiopathic arthritis

G Giancane, A Alongi, S Rosina, J Tibaldi… - Best Practice & …, 2017 - Elsevier
Over the past two decades, the management of juvenile idiopathic arthritis (JIA) has been
revolutionized by the increased tendency toward early aggressive interventions and the …

Comparison between clinical and ultrasound assessment of the ankle region in children with juvenile idiopathic arthritis

S Lanni, DP Marafon, A Civino, A Alongi… - Arthritis Care & …, 2021 - Wiley Online Library
Objective To compare the frequency of joint and tendon disease on ultrasound (US) and
clinical examination, and to investigate agreement between US and clinical evaluation in …

Macrophage activation syndrome in pediatrics

A Alongi, R Naddei, L De Miglio… - Pediatric Allergy and …, 2020 - Wiley Online Library
Macrophage activation syndrome (MAS) is a serious, potentially life‐threatening,
hyperinflammatory condition, which belongs to the spectrum of hemophagocytic …

Drivers of non-zero physician global scores during periods of inactive disease in juvenile idiopathic arthritis

A Alongi, G Giancane, R Naddei, V Natoli, F Ridella… - RMD open, 2022 - rmdopen.bmj.com
Objective To investigate the frequency in which the physician provides a global assessment
of disease activity (PhGA)> 0 and an active joint count (AJC)= 0 in children with juvenile …