Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis

E Kyriazopoulou, T Huet, G Cavalli, A Gori… - The Lancet …, 2021 - thelancet.com
Background Anakinra might improve the prognosis of patients with moderate to severe
COVID-19 (ie, patients requiring oxygen supplementation but not yet receiving organ …

[HTML][HTML] Mapping the human genetic architecture of COVID-19

Writing group Writing group leaders Pathak Gita A. 6 … - Nature, 2021 - nature.com
The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …

Altered gut microbiome composition in HIV infection: causes, effects and potential intervention

A Bandera, I De Benedetto, G Bozzi… - Current opinion in HIV …, 2018 - journals.lww.com
Studying the human host–microbiota interaction suggests that the consequences of HIV
infection on microbial composition can influence immune status in HIV patients. ART …

[HTML][HTML] Gut and airway microbiota dysbiosis and their role in COVID-19 and long-COVID

G Ancona, L Alagna, C Alteri, E Palomba… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota plays a crucial role in human health and disease. Gut dysbiosis is known
to be associated with increased susceptibility to respiratory diseases and modifications in …

Hospital-acquired infections in critically ill patients with COVID-19

G Grasselli, V Scaravilli, D Mangioni, L Scudeller… - Chest, 2021 - Elsevier
Background Few small studies have described hospital-acquired infections (HAIs) occurring
in patients with COVID-19. Research Question What characteristics in critically ill patients …

[HTML][HTML] Long-term consequences of COVID-19: research needs

D Yelin, E Wirtheim, P Vetter, AC Kalil… - The Lancet Infectious …, 2020 - thelancet.com
Weeks and months after the onset of acute COVID-19, people continue to suffer. Paul
Garner, a professor of epidemiology at Liverpool School of Tropical Medicine, UK, wrote on …

[HTML][HTML] SARS-CoV-2-related atypical thyroiditis

I Muller, D Cannavaro, D Dazzi, D Covelli… - The lancet Diabetes & …, 2020 - thelancet.com
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) 1, 2 has seriously affected northern Italy. Preliminary data analysis of patients …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Integrated longitudinal immunophenotypic, transcriptional, and repertoire analyses delineate immune responses in patients with COVID-19

S Notarbartolo, V Ranzani, A Bandera, P Gruarin… - Science …, 2021 - science.org
To understand how a protective immune response against SARS-CoV-2 develops over time,
we integrated phenotypic, transcriptional, and repertoire analyses on PBMCs from patients …

SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines

JE Bowen, YJ Park, C Stewart, JT Brown… - Science …, 2022 - science.org
Numerous safe and effective coronavirus disease 2019 vaccines have been developed
worldwide that use various delivery technologies and engineering strategies. We show here …