Background Necroscopic and surgical studies have suggested that giant cell arteritis (GCA)
may target the aorta and its main branches. Imaging techniques are able to detect large …

Background—Patients with giant-cell arteritis (GCA) who develop a strong acute-phase
response are at low risk of disease-related ischemic events. Methods and Results—To …

Objective Giant cell arteritis (GCA) may involve the aorta. Retrospective studies have
demonstrated a higher prevalence of aortic aneurysm among patients with GCA compared …

Background Positron emission tomography (PET) scan is emerging as a promising imaging
technique to detect large-vessel inflammation in giant cell arteritis (GCA). However, the lack …

Objective To assess whether the intensity of the initial systemic inflammatory response is
able to predict response to therapy in patients with giant cell arteritis (GCA). Methods …

Background Aortic structural damage (ASD) may complicate the course of patients with giant
cell arteritis (GCA). However the frequency and outcome of ASD has not been assessed in …

Background Interferon γ (IFNγ) is considered a seminal cytokine in the pathogenesis of giant
cell arteritis (GCA), but its functional role has not been investigated. We explored changes in …

Background Interleukin 17A (IL-17A) exerts pivotal proinflammatory functions in chronic
inflammatory and autoimmune diseases. Objective To investigate IL-17A expression in …

Objective. To evaluate the association between inflammatory markers and relapse in GCA
patients longitudinally assessed in a clinical trial of infliximab and glucocorticosteroids …

Computed tomography angiography (CTA) detects signs of large-vessel vasculitis (LVV) in
about 67.5% of patients with giant-cell arteritis (GCA) at the time of diagnosis and early …