[HTML][HTML] Cardiovascular and cancer risk with tofacitinib in rheumatoid arthritis

SR Ytterberg, DL Bhatt, TR Mikuls… - … England Journal of …, 2022 - Mass Medical Soc
Background Increases in lipid levels and cancers with tofacitinib prompted a trial of major
adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis …

[PDF][PDF] Postapproval comparative safety study of tofacitinib and biological Disease‐Modifying Antirheumatic drugs: 5‐Year results from a United States–based …

JM Kremer, CO Bingham III, LC Cappelli… - ACR Open …, 2021 - Wiley Online Library
Objective Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis
(RA). We compared 5‐year adverse event (AE) incidence rates (IRs) between patients …

Challenges with quality of race and ethnicity data in observational databases

FCG Polubriaginof, P Ryan, H Salmasian… - Journal of the …, 2019 - academic.oup.com
Objective We sought to assess the quality of race and ethnicity information in observational
health databases, including electronic health records (EHRs), and to propose patient self …

Long-term safety of tofacitinib up to 9.5 years: a comprehensive integrated analysis of the rheumatoid arthritis clinical development programme

SB Cohen, Y Tanaka, X Mariette, JR Curtis, EB Lee… - RMD open, 2020 - rmdopen.bmj.com
Objective Tofacitinib is an oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid
arthritis (RA). We report the largest integrated safety analysis of tofacitinib, as of March 2017 …

Infections in patients with rheumatoid arthritis receiving tofacitinib versus tumour necrosis factor inhibitors: results from the open-label, randomised controlled ORAL …

AR Balanescu, G Citera, V Pascual-Ramos… - Annals of the …, 2022 - ard.bmj.com
Objectives To characterise infections in patients with rheumatoid arthritis (RA) in ORAL
Surveillance. Methods In this open-label, randomised controlled trial, patients with RA …

[BOOK][B] Creating contagious commitment: Applying the tipping point to organizational change

A Shapiro - 2010 - books.google.com
Too often, necessary and technically appropriate change initiatives fall short of expected
gains because leaders fail to involve employees and leverage their perspectives. This …

Effects of vague probabilities and of vague payoffs on preference: A model comparison analysis

C Gonzalez-Vallejo, A Bonazzi, AJ Shapiro - Journal of Mathematical …, 1996 - Elsevier
Preference orders over gambles having vague probabilities or vague payoffs were
investigated. Riskandworthjudgments were also studied in these two vague conditions. A …

Age-based (< 65 vs≥ 65 years) incidence of infections and serious infections with tofacitinib versus biological DMARDs in rheumatoid arthritis clinical trials and the …

KL Winthrop, G Citera, D Gold, D Henrohn… - Annals of the …, 2021 - ard.bmj.com
A randomised, open-label, blinded endpoint post-authorisation safety study (Study
A3921133; NCT02092467; database not locked and subject to change) evaluated the safety …

Unequal before the law: Men, women and the death penalty

A Shapiro - Am. UJ Gender Soc. Pol'y & L., 2000 - HeinOnline
In a landmark death penalty case, McCleskey v. Kemp, defendant Warren McCleskey, a
Black man, appealed his conviction and death sentence4 on the grounds that Georgia's …

Overcoming technical and cultural challenges to delivering equitable care for LGBTQ+ individuals in a rural, underserved area

HL Marney, DK Vawdrey, L Warsame… - Journal of the …, 2022 - academic.oup.com
The lesbian, gay, bisexual, transgender, queer, or questioning (LGBTQ+) community is
vulnerable to health-care disparities. Many health-care organizations are working to collect …