Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma

MC Da Vià, O Dietrich, M Truger, P Arampatzi, J Duell… - Nature medicine, 2021 - nature.com
B cell maturation antigen (BCMA) is a target for various immunotherapies and a biomarker
for tumor load in multiple myeloma (MM). We report a case of irreversible BCMA loss in a …

The role of surgery in the management of recurrent adrenocortical carcinoma

I Erdogan, T Deutschbein, C Jurowich… - The Journal of …, 2013 - academic.oup.com
Context: Surgery is the standard of care for localized adrenocortical carcinomas, but its role
for recurrent disease is not well defined. Objective: Our objective was to evaluate clinical …

Vertebral compression fractures: third-generation dual-energy CT for detection of bone marrow edema at visual and quantitative analyses

B Petritsch, A Kosmala, AM Weng, B Krauss… - Radiology, 2017 - pubs.rsna.org
Purpose To assess the diagnostic performance of a third-generation dual-energy computed
tomographic (CT) virtual noncalcium (VNCa) technique for detection of traumatic bone …

Multiple myeloma and dual-energy CT: diagnostic accuracy of virtual noncalcium technique for detection of bone marrow infiltration of the spine and pelvis

A Kosmala, AM Weng, A Heidemeier, B Krauss, S Knop… - Radiology, 2018 - pubs.rsna.org
Purpose To determine the diagnostic performance of dual-energy computed tomography
(CT) for detection of bone marrow (BM) infiltration in patients with multiple myeloma by using …

Minimal residual disease and imaging‐guided consolidation strategies in newly diagnosed and relapsed refractory multiple myeloma

D Böckle, P Tabares, X Zhou… - British Journal of …, 2022 - Wiley Online Library
Measurement of minimal residual disease (MRD) by next‐generation flow cytometry (NGF)
is an important tool to define deep responses in multiple myeloma (MM). However, little is …

[HTML][HTML] Salvage treatment of adrenocortical carcinoma with trofosfamide

M Kroiss, T Deutschbein, W Schlötelburg… - Hormones and …, 2016 - Springer
Adrenocortical carcinoma (ACC) has a dismal prognosis in advanced stages. Despite
treatment with the adrenal toxicant mitotane and/or aggressive chemotherapy, tumor control …

Quantification of fat fraction in lumbar vertebrae: correlation with age and implications for bone marrow dosimetry in molecular radiotherapy

M Salas-Ramirez, J Tran-Gia… - Physics in Medicine …, 2018 - iopscience.iop.org
Absorbed dose to active bone marrow is a predictor of hematological toxicity in molecular
radiotherapy. Due to the complex composition of bone marrow tissue, the necessity to …

Treatment of refractory adrenocortical carcinoma with thalidomide: analysis of 27 patients from the European Network for the Study of Adrenal Tumours Registry

M Kroiss, T Deutschbein, W Schlötelburg… - Experimental and …, 2019 - thieme-connect.com
Objective Adrenocortical carcinoma (ACC) is a rare malignancy with a dismal prognosis. In
advanced stages, tumour control by mitotane and cytotoxic chemotherapy is often temporary …

[HTML][HTML] Lack of spleen signal on diffusion weighted MRI is associated with high tumor burden and poor prognosis in multiple myeloma: a link to extramedullary …

L Rasche, M Kumar, G Gershner, R Samant… - Theranostics, 2019 - ncbi.nlm.nih.gov
Due to the low frequency of abnormalities affecting the spleen, this organ is often overlooked
during radiological examinations. Here, we report on the unexpected finding, that the spleen …

Efficacy of zoledronic acid in the treatment of nonmalignant painful bone marrow lesions: a triple‐blind, randomized, placebo‐controlled phase III clinical trial …

L Seefried, F Genest, J Baumann… - Journal of Bone and …, 2020 - academic.oup.com
Bone marrow lesions (BML) represent areas of deteriorated bone structure and metabolism
characterized by pronounced water‐equivalent signaling within the trabecular bone on …