[HTML][HTML] Risk factors for multiple sclerosis in the context of Epstein-Barr virus infection

AK Hedström - Frontiers in Immunology, 2023 - frontiersin.org
Compelling evidence indicates that Epstein Barr virus (EBV) infection is a prerequisite for
multiple sclerosis (MS). The disease may arise from a complex interplay between latent EBV …

Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis

AK Hedström, E Sundqvist, M Bäärnhielm, N Nordin… - Brain, 2011 - academic.oup.com
Both genetic and environmental factors display low or modest associations with multiple
sclerosis. Hypothetically, gene–environment interactions may exert much stronger effects. In …

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis

AK Hedström, I Lima Bomfim, L Barcellos… - Neurology, 2014 - AAN Enterprises
Objective: We investigated potential interactions between human leukocyte antigen (HLA)
genotype and body mass index (BMI) status in relation to the risk of developing multiple …

Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk

B Rhead, M Bäärnhielm, M Gianfrancesco… - Neurology …, 2016 - AAN Enterprises
Objective: We sought to estimate the causal effect of low serum 25 (OH) D on multiple
sclerosis (MS) susceptibility that is not confounded by environmental or lifestyle factors or …

[HTML][HTML] Smoking and multiple sclerosis susceptibility

AK Hedström, J Hillert, T Olsson… - European journal of …, 2013 - Springer
Smoking is one of the most established risk factors for multiple sclerosis (MS). The aim of
this study was to investigate how age at smoking debut, duration, intensity and cumulative …

Effect of smoking cessation on multiple sclerosis prognosis

R Ramanujam, AK Hedström, A Manouchehrinia… - JAMA …, 2015 - jamanetwork.com
Importance Smoking tobacco is a well-established risk factor for multiple sclerosis (MS), a
chronic inflammatory disorder of the central nervous system usually characterized by bouts …

Shift work at young age is associated with increased risk for multiple sclerosis

AK Hedström, T Åkerstedt, J Hillert, T Olsson… - Annals of …, 2011 - Wiley Online Library
Objective: Environmental factors play a prominent role in multiple sclerosis (MS) etiology.
The aim of this study was to investigate the potential association between shift work and MS …

Importance of early treatment initiation in the clinical course of multiple sclerosis

A Kavaliunas, A Manouchehrinia… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Objectives: The aim of this study was to identify factors influencing the long-term clinical
progression of multiple sclerosis (MS). A special objective was to investigate whether early …

Treatment options for Epstein-Barr virus-related disorders of the central nervous system

O Andersen, I Ernberg, AK Hedström - Infection and Drug …, 2023 - Taylor & Francis
Abstract Epstein-Barr virus (EBV), a causative agent for several types of lymphomas and
mucosal cancers, is a human lymphotropic herpesvirus with the capacity to establish lifelong …

Alcohol as a modifiable lifestyle factor affecting multiple sclerosis risk

AK Hedström, J Hillert, T Olsson, L Alfredsson - JAMA neurology, 2014 - jamanetwork.com
Importance Alcohol consumption may be a modifiable lifestyle factor that affects the risk of
developing multiple sclerosis (MS). Results of previous studies have been inconsistent …