The contribution of adipose tissue and adipokines to inflammation in joint diseases

E Toussirot, G Streit, D Wendling - Current medicinal chemistry, 2007 - ingentaconnect.com
Adipokines are proteins produced by white adipose tissue, which is an active secretory
organ. Regulation of immune and inflammatory responses is among the multiple …

Physical activity in patients with rheumatoid arthritis

F Verhoeven, N Tordi, C Prati, C Demougeot, F Mougin… - Joint bone spine, 2016 - Elsevier
Introduction Rheumatoid arthritis (RA) is the most common chronic inflammatory joint
disease and is associated with an excess risk of cardiovascular disease. For the general …

Microvascular endothelial dysfunction in rheumatoid arthritis

R Bordy, P Totoson, C Prati, C Marie… - Nature Reviews …, 2018 - nature.com
The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor …

ASAS/EULAR recommendations for the management of ankylosing spondylitis

J Zochling, D van der Heijde… - Annals of the …, 2006 - ard.bmj.com
Objective: To develop evidence based recommendations for the management of ankylosing
spondylitis (AS) as a combined effort of the 'ASsessment in AS'international working group …

Treatment of severe rheumatoid arthritis by anti-interleukin 6 monoclonal antibody.

D Wendling, E Racadot, J Wijdenes - The Journal of rheumatology, 1993 - europepmc.org
Interleukin 6 (IL-6) appears to be a potential mediator of inflammation that may contribute to
the pathogenesis of joint inflammation in RA. Anti-IL-6 monoclonal antibodies (Mab) may …

Drug-specific risk of non-tuberculosis opportunistic infections in patients receiving anti-TNF therapy reported to the 3-year prospective French RATIO registry

D Salmon-Céron, F Tubach, O Lortholary… - Annals of the …, 2011 - ard.bmj.com
Background Anti-tumour necrosis factor (TNF) therapy may be associated with opportunistic
infections (OIs). Objective To describe the spectrum of non-tuberculosis OIs associated with …

The DESIR cohort: a 10-year follow-up of early inflammatory back pain in France: study design and baseline characteristics of the 708 recruited patients

M Dougados, MA d'Agostino, J Benessiano… - Joint bone spine, 2011 - Elsevier
OBJECTIVES: The French Society of Rheumatology has initiated a large national
multicenter, longitudinal, prospective follow-up of patients presenting with early inflammatory …

Non–TNF-targeted biologic vs a second anti-TNF drug to treat rheumatoid arthritis in patients with insufficient response to a first anti-TNF drug: a randomized clinical …

JE Gottenberg, O Brocq, A Perdriger, S Lassoued… - Jama, 2016 - jamanetwork.com
Importance One-third of patients with rheumatoid arthritis show inadequate response to
tumor necrosis factor α (TNF-α) inhibitors; little guidance on choosing the next treatment …

Rheumatoid factor and disease activity are independent predictors of lymphoma in primary Sjögren's syndrome

G Nocturne, A Virone, WF Ng, V Le Guern… - Arthritis & …, 2016 - Wiley Online Library
Objective To define parameters predictive of lymphoma development in patients with
primary Sjögren's syndrome (SS). Methods A multicenter case–control survey was …

Effect of tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy: a randomized clinical trial

V Devauchelle-Pensec, G Carvajal-Alegria, E Dernis… - Jama, 2022 - jamanetwork.com
Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …