Oleate abrogates palmitate-induced lipotoxicity and proinflammatory response in human bone marrow-derived mesenchymal stem cells and osteoblastic cells
C Gillet, D Spruyt, S Rigutto, A Dalla Valle… - …, 2015 - academic.oup.com
Osteoporosis is a metabolic bone disease associated with unequilibrated bone remodeling
resulting from decreased bone formation and/or increased bone resorption, leading to …
resulting from decreased bone formation and/or increased bone resorption, leading to …
Decreased pool of mesenchymal stem cells is associated with altered chemokines serum levels in atrophic nonunion fractures
M Mathieu, S Rigutto, A Ingels, D Spruyt, N Stricwant… - Bone, 2013 - Elsevier
Nonunion fractures can cause severe dysfunction and are often difficult to treat mainly due to
a poor understanding of their physiopathology. Although many aspects of impaired fracture …
a poor understanding of their physiopathology. Although many aspects of impaired fracture …
Osteonecrosis of the femoral head: lipotoxicity exacerbation in MSC and modifications of the bone marrow fluid
C Gillet, A Dalla Valle, N Gaspard, D Spruyt… - …, 2017 - academic.oup.com
Osteonecrosis of the femoral head (ON) is a multifactorial bone disease that can evolve to a
progressive destruction of the hip joint. Different pathogenic processes have been proposed …
progressive destruction of the hip joint. Different pathogenic processes have been proposed …
Serum calprotectin (S100A8/A9): A promising biomarker in diagnosis and follow-up in different subgroups of juvenile idiopathic arthritis
C La, PQ Lê, A Ferster, L Goffin, D Spruyt… - RMD open, 2021 - rmdopen.bmj.com
Introduction In the management of juvenile idiopathic arthritis (JIA), there is a lack of
diagnostic and prognostic biomarkers. This study assesses the use of serum calprotectin …
diagnostic and prognostic biomarkers. This study assesses the use of serum calprotectin …
[HTML][HTML] Induction of stearoyl-CoA 9-desaturase 1 protects human mesenchymal stromal cells against palmitic acid-induced lipotoxicity and inflammation
A Dalla Valle, P Vertongen, D Spruyt… - Frontiers in …, 2019 - frontiersin.org
In bone diseases such as osteonecrosis and osteoporosis, a shift toward a preferential
differentiation of mesenchymal stromal cells (MSC) into adipocytes at the expense of the …
differentiation of mesenchymal stromal cells (MSC) into adipocytes at the expense of the …
Antibodies against carbamylated proteins: prevalence and associated disease characteristics in Belgian patients with rheumatoid arthritis or other rheumatic diseases
P Sidiras, D Spruyt, V Gangji, V Imbault… - Scandinavian journal …, 2021 - Taylor & Francis
Objectives: Anti-carbamylated protein antibodies (anti-CarP) are reported to be associated
with increased disease activity and with more severe joint damage in rheumatoid arthritis …
with increased disease activity and with more severe joint damage in rheumatoid arthritis …
Place du dosage de la calprotectine sérique comme biomarqueur d'intérêt dans l'arthrite juvénile idiopathique
C La, P Stordeur, J Smet, D Franchimont… - Revue du …, 2016 - Elsevier
Nous manquons pour l'arthrite juvénile idiopathique (AJI) de marqueurs spécifiques de
diagnostic, de pronostic ou de réponse thérapeutique. La calprotectine est une protéine …
diagnostic, de pronostic ou de réponse thérapeutique. La calprotectine est une protéine …
[CITATION][C] Bone and bone marrow; interactions
D Spruyt, C Gillet, J Rasschaert - Encyclopedia of Endocrine …, 2018 - difusion.ulb.ac.be
[CITATION][C] Oleic acid protects hMSC from healthy donors and osteonecrotic patients against lipotoxicity by inducing intracellular lipid droplet formation and …
C Gillet, D Spruyt, J Berlier… - JOURNAL OF …, 2014 - … ST, HOBOKEN 07030-5774, NJ USA
[CITATION][C] Role of saturated and monounsaturated fatty acids on function and survival of human mesenchymal stem cells and differentiated osteoblasts.
C Gillet, J Berlier, D Spruyt, S Rigutto, A Dalla Valle… - 2013 - difusion.ulb.ac.be