Prognosis of seronegative patients in a large prospective cohort of patients with early inflammatory arthritis

L Barra, JE Pope, JE Orav, G Boire, B Haraoui… - The Journal of …, 2014 - jrheum.org
Objective. Rheumatoid factor (RF) and anticitrullinated protein antibodies (ACPA) are
believed to be associated with more severe rheumatoid arthritis; however, studies in early …

Determining the minimally important difference in the clinical disease activity index for improvement and worsening in early rheumatoid arthritis patients

JR Curtis, S Yang, L Chen, JE Pope… - Arthritis care & …, 2015 - Wiley Online Library
Objective Simplified measures to quantify rheumatoid arthritis (RA) disease activity are
increasingly used. The minimum clinically important differences (MCID) for some measures …

The comparative effectiveness of oral versus subcutaneous methotrexate for the treatment of early rheumatoid arthritis

GS Hazlewood, JC Thorne, JE Pope, D Lin… - Annals of the …, 2016 - ard.bmj.com
Objective To determine the comparative effectiveness of oral versus subcutaneous
methotrexate (MTX) as initial therapy for patients with early rheumatoid arthritis (ERA) …

Treatment preferences of patients with early rheumatoid arthritis: a discrete-choice experiment

GS Hazlewood, C Bombardier, G Tomlinson… - …, 2016 - academic.oup.com
Objective. To quantify the preferences of patients with early RA (ERA) with the benefits and
harms of DMARDs. Methods. We assessed patients' preferences using a discrete-choice …

Identifying flares in rheumatoid arthritis: reliability and construct validation of the OMERACT RA Flare Core Domain Set

VP Bykerk, CO Bingham, EH Choy, D Lin, R Alten… - RMD open, 2016 - rmdopen.bmj.com
Objective To evaluate the reliability of concurrent flare identification using 3 methods
(patient, rheumatologist and Disease Activity Score (DAS) 28 criteria), and construct validity …

Overweight, obesity, and the likelihood of achieving sustained remission in early rheumatoid arthritis: results from a multicenter prospective cohort study

E Schulman, SJ Bartlett, O Schieir… - Arthritis care & …, 2018 - Wiley Online Library
Objective Obesity is implicated in rheumatoid arthritis (RA) development, severity, outcomes,
and treatment response. We estimated the independent effects of overweight and obesity on …

Effect of age at menopause on disease presentation in early rheumatoid arthritis: results from the Canadian Early Arthritis Cohort

LE Wong, WT Huang, JE Pope, B Haraoui… - Arthritis care & …, 2015 - Wiley Online Library
Objective Studies suggest that hormonal states affect disease characteristics in women with
rheumatoid arthritis (RA). This study investigated how age at menopause affects disease in …

Earlier time to remission predicts sustained clinical remission in early rheumatoid arthritis—results from the Canadian Early Arthritis Cohort (CATCH)

B Kuriya, J Xiong, G Boire, B Haraoui… - The Journal of …, 2014 - jrheum.org
Objective. To evaluate the prevalence and predictive factors of sustained remission in an
early rheumatoid arthritis (ERA) population. Predictive factors of sustained remission in ERA …

[HTML][HTML] Heterogeneous disease trajectories explain variable radiographic, function and quality of life outcomes in the Canadian Early Arthritis Cohort (CATCH)

C Barnabe, Y Sun, G Boire, CA Hitchon, B Haraoui… - PLoS …, 2015 - journals.plos.org
Our objective was to identify distinct trajectories of disease activity state (DAS) and assess
variation in radiographic progression, function and quality of life over the first two years of …

Self-reported comorbidity is common in early inflammatory arthritis and associated with poorer function and worse arthritis disease outcomes: results from the …

CA Hitchon, G Boire, B Haraoui, E Keystone… - …, 2016 - academic.oup.com
Objective. Comorbid medical conditions may influence treatment and contribute to poor
outcomes in early RA. We aimed to assess the association of baseline comorbidity with …