Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis

E Kyriazopoulou, T Huet, G Cavalli, A Gori… - The Lancet …, 2021 - thelancet.com
Background Anakinra might improve the prognosis of patients with moderate to severe
COVID-19 (ie, patients requiring oxygen supplementation but not yet receiving organ …

Macrophage activation syndrome

A Ravelli, S Davė, F Minoia, A Martini… - Hematology …, 2015 - hemonc.theclinics.com
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2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

A Ravelli, F Minoia, S Davė, AC Horne… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop criteria for the classification of macrophage activation syndrome (MAS)
in patients with systemic juvenile idiopathic arthritis (JIA). Methods A multistep process …

Clinical features and correct diagnosis of macrophage activation syndrome

RQ Cron, S Davi, F Minoia, A Ravelli - Expert review of clinical …, 2015 - Taylor & Francis
Macrophage activation syndrome (MAS) is increasingly recognized among febrile
hospitalized patients. Clinically, MAS resembles multiorgan dysfunction and shock …

Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of …

F Minoia, S Davė, AC Horne, E Demirkaya… - Arthritis & …, 2014 - Wiley Online Library
Objective To describe the clinical, laboratory, and histopathologic features, current
treatment, and outcome of patients with macrophage activation syndrome (MAS) …

Anakinra combined with methylprednisolone in patients with severe COVID-19 pneumonia and hyperinflammation: An observational cohort study

G Bozzi, D Mangioni, F Minoia, S Aliberti… - Journal of Allergy and …, 2021 - Elsevier
Background Immunomodulants have been proposed to mitigate severe acute respiratory
syndrome coronavirus 2–induced cytokine storm, which drives acute respiratory distress …

Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

S Davė, F Minoia, A Pistorio, AC Horne… - Arthritis & …, 2014 - Wiley Online Library
Objective To compare the capacity of the 2004 diagnostic guidelines for hemophagocytic
lymphohistiocytosis (HLH‐2004) with the capacity of the preliminary diagnostic guidelines …

Effect of biologic therapy on clinical and laboratory features of macrophage activation syndrome associated with systemic juvenile idiopathic arthritis

GS Schulert, F Minoia, J Bohnsack… - Arthritis care & …, 2018 - Wiley Online Library
Objective To assess performance of the 2016 macrophage activation syndrome (MAS)
classification criteria for patients with systemic juvenile idiopathic arthritis (JIA) who develop …

Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis

F Minoia, F Bovis, S Davė, AC Horne… - Annals of the …, 2019 - ard.bmj.com
Objective To develop and validate a diagnostic score that aids in identifying macrophage
activation syndrome (MAS) in patients with systemic juvenile idiopathic arthritis (sJIA) …

[HTML][HTML] Use of anakinra in severe COVID-19: a case report

G Filocamo, D Mangioni, P Tagliabue, S Aliberti… - International Journal of …, 2020 - Elsevier
Coronavirus disease 19 is a global healthcare emergency with a high lethality rate. Relevant
inflammatory cytokine storm is associated with severity of disease, and IL1 inhibition is a …