[HTML][HTML] Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value

MAM van Boekel, ER Vossenaar… - Arthritis Research & …, 2001 - Springer
The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is
often difficult to diagnose RA in very early stages of the disease. A disease-specific …

The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

GA Schellekens, H Visser, BAW De Jong… - … : Official Journal of …, 2000 - Wiley Online Library
Objective Since modern treatment of rheumatoid arthritis (RA) is shifting toward aggressive
antirheumatic therapy in an early phase of the disease, diagnostic tests with high specificity …

The prognostic value of anti–cyclic citrullinated peptide antibody in patients with recent‐onset rheumatoid arthritis

EJJA Kroot, BAW De Jong… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To study the predictive value of anti–cyclic citrullinated peptide antibody (anti‐
CCP) in patients with recent‐onset rheumatoid arthritis (RA). Methods Outcome in terms of …

Down‐titration and discontinuation strategies of tumour necrosis factor–blocking agents for rheumatoid arthritis in patients with low disease activity

LM Verhoef, BJF Van Den Bemt… - Cochrane Database …, 2019 - cochranelibrary.com
Background Anti–tumour necrosis factor (TNF) agents are effective in treating people with
rheumatoid arthritis (RA), but are associated with (dose‐dependent) adverse effects and …

[PDF][PDF] Little evidence for usefulness of biomarkers for predicting successful dose reduction or discontinuation of a biologic agent in rheumatoid arthritis: a systematic …

L Tweehuysen, CH van den Ende… - Arthritis & …, 2017 - Wiley Online Library
Objective To systematically review studies addressing prediction of successful dose
reduction or discontinuation of a biologic agent in rheumatoid arthritis (RA). Methods …

Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis

TRDJ Radstake, M Svenson, AM Eijsbouts… - Annals of the …, 2009 - ard.bmj.com
Background: Tumour necrosis factor α (TNFα) neutralising antibody constructs are
increasingly being used to treat rheumatoid arthritis (RA). Objective: To determine potential …

Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus

M Vikkula, ECM Madman, VCH Lui, NI Zhidkova… - Cell, 1995 - cell.com
Identifying mutations that cause specific osteochondrodysplasias will provide novel insights
into the function of genes that are essential for skeletal morphogenesis. We report here that …

Risk factors for surgical site infections and other complications in elective surgery in patients with rheumatoid arthritis with special attention for anti-tumor necrosis …

AA den Broeder, MCW Creemers, J Fransen… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To identify risk factors for surgical site infection (SSI) in patients with
rheumatoid arthritis (RA) with special attention for anti-tumor necrosis factor (anti-TNF) …

Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis

MC Vonk, Z Marjanovic, FHJ van den Hoogen… - Annals of the …, 2008 - ard.bmj.com
Objective: Systemic sclerosis (SSc) is a generalised autoimmune disease, causing morbidity
and a reduced life expectancy, especially in patients with rapidly progressive diffuse …

Disease activity guided dose reduction and withdrawal of adalimumab or etanercept compared with usual care in rheumatoid arthritis: open label, randomised …

N van Herwaarden, A van der Maas, MJM Minten… - bmj, 2015 - bmj.com
Objective To evaluate whether a disease activity guided strategy of dose reduction of two
tumour necrosis factor (TNF) inhibitors, adalimumab or etanercept, is non-inferior in …