Congenital defects of platelet function

G Podda, EA Femia, M Pugliano, M Cattaneo - Platelets, 2012 - Taylor & Francis
Congenital abnormalities of platelet function disorder (PFD) are associated with the
heightened risk for bleeding. Typically, patients with PFDs have mucocutaneous bleeding of …

Enoxaparin for thromboprophylaxis in hospitalized COVID‐19 patients: the X‐COVID‐19 randomized trial

N Morici, GM Podda, S Birocchi… - European journal of …, 2022 - Wiley Online Library
Background It is uncertain whether higher doses of anticoagulants than recommended for
thromboprophylaxis are necessary in COVID‐19 patients hospitalized in general wards …

[HTML][HTML] Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: a communication from the Platelet Physiology SSC

P Gresele, S Orsini, P Noris, E Falcinelli… - Journal of Thrombosis …, 2020 - Elsevier
Background Careful assessment of bleeding history is the first step in the evaluation of
patients with mild/moderate bleeding disorders, and the use of a bleeding assessment tool …

The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet …

P Gresele, E Falcinelli, L Bury, A Pecci… - … of Thrombosis and …, 2021 - Wiley Online Library
Abstract Background The ISTH Bleeding Assessment Tool (ISTH‐BAT) has been validated
for clinical screening of suspected von Willebrand disease (VWD) and for bleeding …

Clearance of circulating activated platelets in polycythemia vera and essential thrombocythemia

N Maugeri, S Malato, EA Femia… - Blood, The Journal …, 2011 - ashpublications.org
Essential thrombocythemia (ET) and polycythemia vera (PV) are characterized by persistent
platelet activation. The mechanisms involved in their clearance are poorly characterized. In …

Comparison of different procedures to prepare platelet-rich plasma for studies of platelet aggregation by light transmission aggregometry

EA Femia, M Pugliano, G Podda, M Cattaneo - Platelets, 2012 - Taylor & Francis
Light transmission aggregometry (LTA), the gold standard for the study of patients with
defects of platelet function, is a poorly standardized technique. The guidelines that have …

[HTML][HTML] Blood cell-bound C4d as a marker of complement activation in patients with the antiphospholipid syndrome

PA Lonati, M Scavone, M Gerosa, MO Borghi… - Frontiers in …, 2019 - frontiersin.org
Antiphospholipid syndrome (APS) is a chronic and disabling condition characterized by
recurrent thrombosis and miscarriages mediated by antibodies against phospholipid …

Impact of gene polymorphisms, platelet reactivity, and the SYNTAX score on 1-year clinical outcomes in patients with non–ST-segment elevation acute coronary …

T Palmerini, P Calabrò, F Piscione, S De Servi… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The aim of this study was to investigate the association between high on-
treatment platelet reactivity (HPR) and the SYNTAX (Synergy Between Percutaneous …

[HTML][HTML] Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients

CA Di Buduo, MA Alberelli, AC Glembotsky, G Podda… - Scientific reports, 2016 - nature.com
Abstract The Gray Platelet Syndrome (GPS) is a rare inherited bleeding disorder
characterized by deficiency of platelet α-granules, macrothrombocytopenia and marrow …

Megakaryocytic emperipolesis and platelet function abnormalities in five patients with gray platelet syndrome

LM Larocca, PG Heller, G Podda, N Pujol-Moix… - Platelets, 2015 - Taylor & Francis
The gray platelet syndrome (GPS) is a rare congenital platelet disorder characterized by
mild to moderate bleeding diathesis, macrothrombocytopenia and lack of azurophilic α …