OBJECTIVE: To evaluate the cardiovascular risk profile of spondylarthropathy patients,
particularly ankylosing spondylitis and psoriatic arthritis. METHODS: A Pubmed literature …

A well-known complication in patients with ankylosing spondylitis (AS) is the development of
localised vertebral or discovertebral lesions of the spine, which was first described by …

Mounting evidence reveals evident sex differences in physiology, disease presentation and
response to medication in axial SpA (axSpA). Unfortunately these data are often neglected …

To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Objective Autoantibodies have been demonstrated in single serum samples from healthy
subjects up to 10 years before they developed rheumatoid arthritis (RA). However, the time …

To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-
analysis of two published genome-wide association (GWA) studies totaling 3,393 cases and …

Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting primarily
the spine and pelvis. In addition to HLA-B* 27 alleles, 12 loci have previously been identified …

To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …

Background Anti-citrullinated protein antibodies (ACPA) are associated with increased risk
for rheumatoid arthritis. Objective To investigate the effect of the presence and levels of …

Background: The anti-cyclic citrullinated peptide (CCP) test has a high sensitivity and
specificity for rheumatoid arthritis, although CCP is not the physiological target of the …