High-resolution musculoskeletal ultrasound (MSUS) has been increasingly employed in
daily rheumatological practice and in clinical research. In rheumatoid arthritis (RA), MSUS …

Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease
characterized by sustained synovitis. Recently, several studies have proposed neutrophils …

Despite the enthusiastic progresses in the field of rheumatoid arthritis pharmacotherapy the
presence of prognostic factors associated with an unfavorable outcome and the …

Objectives. Adalimumab, etanercept and infliximab are effective TNF inhibitors (TNFis) in the
treatment of RA, but no randomized clinical trials have compared the three agents. Prior …

Background The use of TNF-inhibitors and/or the IL-6 receptor antagonist, tocilizumab, in
rheumatoid arthritis (RA) have pleiotropic effects that also involve circulating B-cells. The …

Objectives. B cells play an important role in the perpetuation of RA, particularly as
autoantibody-producing cells. The ICs that further develop deposit in the joints and …

Objectives. To compare the effectiveness of TNF inhibitors (TNFi) and tocilizumab in
rheumatoid arthritis (RA) treatment, according to different response criteria. Methods. We …

Objective. B cells play important roles in rheumatoid arthritis (RA). Given the beneficial effect
of B cell depletion therapy in RA as well as the observed alterations in B cell subpopulations …

Objective Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder with a
global prevalence of approximately 0.5–1%. Patients with RA are at an increased risk of …

Biobank saliva sample quality depends on specific criteria applied to collection, processing,
and storage. In spite of the growing interest in saliva as a diagnostic fluid, few biobanks …