CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
M Edinger, P Hoffmann, J Ermann, K Drago… - Nature medicine, 2003 - nature.com
Mature donor T cells cause graft-versus-host disease (GVHD), but they are also the main
mediators of the beneficial graft-versus-tumor (GVT) activity of allogeneic bone marrow …
mediators of the beneficial graft-versus-tumor (GVT) activity of allogeneic bone marrow …
Donor-type CD4+CD25+ Regulatory T Cells Suppress Lethal Acute Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation
P Hoffmann, J Ermann, M Edinger… - The Journal of …, 2002 - rupress.org
Acute graft-versus-host disease (aGVHD) is still a major obstacle in clinical allogeneic bone
marrow (BM) transplantation. CD4+ CD25+ regulatory T (Treg) cells have recently been …
marrow (BM) transplantation. CD4+ CD25+ regulatory T (Treg) cells have recently been …
[PDF][PDF] American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 recommendations for the …
Objective To provide evidence‐based recommendations for the treatment of patients with
ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). Methods A …
ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). Methods A …
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
Abstract CD4+ CD25+ regulatory T (Treg) cells are potent modulators of alloimmune
responses. In murine models of allogeneic bone marrow transplantation, adoptive transfer of …
responses. In murine models of allogeneic bone marrow transplantation, adoptive transfer of …
The subpopulation of CD4+ CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
V Szanya, J Ermann, C Taylor, C Holness… - The Journal of …, 2002 - journals.aai.org
Abstract Recently, CD4+ CD25+ T cells have been implicated in the control of diabetes,
suggesting that the inflamed islets of Langerhans in prediabetic NOD mice are under …
suggesting that the inflamed islets of Langerhans in prediabetic NOD mice are under …
Immune cell profiling to guide therapeutic decisions in rheumatic diseases
Biomarkers are needed to guide treatment decisions for patients with rheumatic diseases.
Although the phenotypic and functional analysis of immune cells is an appealing strategy for …
Although the phenotypic and functional analysis of immune cells is an appealing strategy for …
An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease
There is a clinical need for new, more effective treatments for chronic and debilitating
inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis …
inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis …
[HTML][HTML] Recognizing axial spondyloarthritis: a guide for primary care
Axial spondyloarthritis (axSpA) is an important cause of chronic low back pain and affects
approximately 1% of the US population. The back pain associated with axSpA has a …
approximately 1% of the US population. The back pain associated with axSpA has a …
The intestinal microbiome and skeletal fitness: Connecting bugs and bones
JF Charles, J Ermann, AO Aliprantis - Clinical Immunology, 2015 - Elsevier
Recent advances have dramatically increased our understanding of how organ systems
interact. This has been especially true for immunology and bone biology, where the term …
interact. This has been especially true for immunology and bone biology, where the term …
Autoimmune diseases: genes, bugs and failed regulation
J Ermann, CG Fathman - Nature immunology, 2001 - nature.com
In this Overview, common themes of the accompanying News & Views on RA, SLE, IDDM,
thyroiditis and MS are discussed. A unifying concept for the development of these and other …
thyroiditis and MS are discussed. A unifying concept for the development of these and other …