Damage-associated molecular pattern (DAMP) molecules have been introduced as
important proinflammatory factors of innate immunity. One example known for many years to …

Abstract S100A8 and S100A9 are novel members of the group of damage–associated
molecular pattern molecules (DAMP) which are early amplifiers of innate immune responses …

Alarmins are endogenous molecules that are constitutively available and released upon
tissue damage and activate the immune system. Current evidence indicates that …

To identify new components that regulate the inflammatory cascade during sepsis, we
characterized the functions of myeloid-related protein-8 (Mrp8, S100A8) and myeloid-related …

Accumulation of myeloid-derived suppressor cells (MDSCs) associated with inhibition of
dendritic cell (DC) differentiation is one of the major immunological abnormalities in cancer …

Myeloid-related protein (MRP) 8 and MRP14, two members of the S100 family expressed in
myelomonocytic cells, have been ascribed some extracellular functions, eg antimicrobial …

Abstract Allergies to nickel (Ni2+) are the most frequent cause of contact hypersensitivity
(CHS) in industrialized countries. The efficient development of CHS requires both a T …

The role of the pore-forming Staphylococcus aureus toxin Panton-Valentine leukocidin
(PVL) in severe necrotizing diseases is debated due to conflicting data from epidemiological …

Objective To analyze which physiologic stimuli induce secretion of myeloid‐related protein 8
(MRP8) and MRP14, two S100 proteins expressed in neutrophils and monocytes, and to …

Three members of the S100 family of calcium-binding proteins comprise a new group of
proinflammatory molecules released by phagocytes. A novel inflammatory syndrome …