User profiles for "author:Katie Tuckwell"

Katie Tuckwell

Regeneron
Verified email at regeneron.com
Cited by 2581

[HTML][HTML] Trial of tocilizumab in giant-cell arteritis

JH Stone, K Tuckwell, S Dimonaco… - … England Journal of …, 2017 - Mass Medical Soc
Background Giant-cell arteritis commonly relapses when glucocorticoids are tapered, and
the prolonged use of glucocorticoids is associated with side effects. The effect of the …

[HTML][HTML] Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial

IO Rosas, G Diaz, RL Gottlieb, SM Lobo… - Intensive care …, 2021 - Springer
Purpose Trials of tocilizumab in patients with severe COVID-19 pneumonia have
demonstrated mixed results, and the role of tocilizumab in combination with other treatments …

[PDF][PDF] Efficacy, safety, and pharmacodynamic effects of the Bruton's tyrosine kinase inhibitor fenebrutinib (GDC‐0853) in systemic lupus erythematosus: results of a …

D Isenberg, R Furie, NS Jones, P Guibord… - Arthritis & …, 2021 - Wiley Online Library
Objective Fenebrutinib (GDC‐0853) is a noncovalent, oral, and highly selective inhibitor of
Bruton's tyrosine kinase (BTK). The efficacy, safety, and pharmacodynamics of fenebrutinib …

[HTML][HTML] Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid …

C Gabay, IB McInnes, A Kavanaugh… - Annals of the …, 2016 - ard.bmj.com
Objective Compare changes in lipids and lipid-associated cardiovascular (CV) risk markers
in patients with rheumatoid arthritis (RA) treated with tocilizumab or adalimumab. Methods …

[PDF][PDF] Fenebrutinib versus placebo or Adalimumab in rheumatoid arthritis: A randomized, Double‐Blind, phase II trial

S Cohen, K Tuckwell, TR Katsumoto… - Arthritis & …, 2020 - Wiley Online Library
Objective To evaluate fenebrutinib, an oral and highly selective noncovalent inhibitor of
Bruton's tyrosine kinase (BTK), in patients with active rheumatoid arthritis (RA). Methods …

Corticosteroid-related adverse events in patients with giant cell arteritis: a claims-based analysis

MS Broder, K Sarsour, E Chang, N Collinson… - Seminars in Arthritis and …, 2016 - Elsevier
Objective Corticosteroids (CS) are standard treatment for giant cell arteritis (GCA), but
concerns persist over toxicities associated with long-term use. In this retrospective study of …

Serious adverse effects associated with glucocorticoid therapy in patients with giant cell arteritis (GCA): a nested case–control analysis

JC Wilson, K Sarsour, N Collinson, K Tuckwell… - Seminars in arthritis and …, 2017 - Elsevier
Objective Giant cell arteritis (GCA) is an inflammatory vasculitis preferentially affecting large
and medium-sized arteries. High-dose oral glucocorticoids (GCs) are the mainstay of GCA …

[HTML][HTML] Glucocorticoid dosages and Acute‐Phase reactant levels at giant cell arteritis flare in a randomized trial of tocilizumab

JH Stone, K Tuckwell, S Dimonaco… - Arthritis & …, 2019 - Wiley Online Library
Objective This study was undertaken to evaluate glucocorticoid dosages and serologic
findings in patients with giant cell arteritis (GCA) flares. Methods Patients with GCA were …

Newly diagnosed vs. relapsing giant cell arteritis: baseline data from the GiACTA trial

K Tuckwell, N Collinson, S Dimonaco… - Seminars in arthritis and …, 2017 - Elsevier
Objective To report entry criteria and clinical features of patients with newly diagnosed and
relapsing giant cell arteritis (GCA) enrolled in a randomized trial of tocilizumab, an …

[HTML][HTML] Risk associated with cumulative oral glucocorticoid use in patients with giant cell arteritis in real-world databases from the USA and UK

S Gale, JC Wilson, J Chia, H Trinh, K Tuckwell… - Rheumatology and …, 2018 - Springer
Introduction Treatment of giant cell arteritis (GCA) involves immediate initiation of high-dose
glucocorticoid therapy with slow tapering of the dose over many months. Chronic exposure …