Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial

MI Lopes, LP Bonjorno, MC Giannini, NB Amaral… - RMD open, 2021 - rmdopen.bmj.com
Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19
results in better outcomes. Design We present the results of a randomised, double-blinded …

Impacts of environmental values on tourism motivation: The case of FICA, Brazil

H Kim, MC Borges, J Chon - Tourism management, 2006 - Elsevier
The city of Goias, Brazil, recently launched the International Festival of Environmental Film
and Video (FICA) in an attempt to increase tourism revenue and foster an awareness of …

Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation

CMS Silva, CWS Wanderley, FP Veras… - Blood, The Journal …, 2021 - ashpublications.org
Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly
correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are …

[HTML][HTML] IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population

DC Nascimento, PH Melo, AR Pineros… - Nature …, 2017 - nature.com
Patients who survive sepsis can develop long-term immune dysfunction, with expansion of
the regulatory T (Treg) cell population. However, how Treg cells proliferate in these patients …

Early neuromuscular electrical stimulation in addition to early mobilization improves functional status and decreases hospitalization days of critically ill patients

DR Campos, TBC Bueno, JSGG Anjos… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: To evaluate the impact of the additional use of early neuromuscular electrical
stimulation (NMES) on an early mobilization (EM) protocol. DESIGN: Randomized controlled …

Beneficial effects of colchicine for moderate to severe COVID-19: an interim analysis of a randomized, double-blinded, placebo controlled clinical trial

MIF Lopes, LP Bonjorno, MC Giannini, NB Amaral… - MedRxiv, 2020 - medrxiv.org
Introduction Neutrophilia and high levels of proinflammatory cytokines and other mediators
of inflammation are common finds in patients with severe acute respiratory syndrome due to …

[HTML][HTML] Antioxidant Activity of an Aqueous Leaf Extract from Uncaria tomentosa and Its Major Alkaloids Mitraphylline and Isomitraphylline in Caenorhabditis elegans

B C. Azevedo, M Roxo, M C. Borges, H Peixoto… - Molecules, 2019 - mdpi.com
Uncaria tomentosa (Rubiaceae) has a recognized therapeutic potential against various
diseases associated with oxidative stress. The aim of this research was to evaluate the …

Clinical evaluation of the NS1 antigen‐capture ELISA for early diagnosis of dengue virus infection in Brazil

LA Castro‐Jorge, PRL Machado… - Journal of medical …, 2010 - Wiley Online Library
The fact that the diagnosis of infection with dengue virus is usually made by detecting IgM
antibodies during the convalescent phase of the disease interferes with disease …

[HTML][HTML] Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control

PMM Garibaldi, NN Ferreira, GR Moraes… - Brazilian Journal of …, 2021 - SciELO Brasil
ABSTRACT SARS-CoV-2 has a high risk of outbreak in long-term skilled nursing facilities
(SNF). Coronavirus disease (COVID-19) has high mortality rates among the elderly with …

Legionella longbeachae Is Immunologically Silent and Highly Virulent In Vivo

LM Massis, MA Assis-Marques… - The Journal of …, 2017 - academic.oup.com
Abstract Background. Legionella longbeachae (Llo) and Legionella pneumophila (Lpn) are
the most common pneumonia-causing agents of the genus. Although both species can be …